scriptaid has been researched along with Breast Cancer in 2 studies
scriptide: provokes translocation of GLUT4 to increase glucose uptake; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a significant fraction of breast cancers, this loss of expression is a result of epigenetic mechanisms, such as DNA methylation and histone deacetylation, within the α-ER promoter." | 5.38 | Scriptaid effects on breast cancer cell lines. ( Gabellini, C; Giacinti, C; Giacinti, L; Giordano, A; Lopez, M; Rizzuto, E, 2012) |
| "Scriptaid treatment of three ER negative cell lines, MDA-MB-231, MDA-MB-435 and Hs578t, resulted in significant growth inhibition and increased acetylation of H3 and H4 histone tails." | 5.32 | A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine. ( Davidson, NE; Keen, JC; Mack, KM; Pettit, C; Sharma, D; Smith, D; Yan, L, 2003) |
| "In a significant fraction of breast cancers, this loss of expression is a result of epigenetic mechanisms, such as DNA methylation and histone deacetylation, within the α-ER promoter." | 1.38 | Scriptaid effects on breast cancer cell lines. ( Gabellini, C; Giacinti, C; Giacinti, L; Giordano, A; Lopez, M; Rizzuto, E, 2012) |
| "Scriptaid treatment of three ER negative cell lines, MDA-MB-231, MDA-MB-435 and Hs578t, resulted in significant growth inhibition and increased acetylation of H3 and H4 histone tails." | 1.32 | A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine. ( Davidson, NE; Keen, JC; Mack, KM; Pettit, C; Sharma, D; Smith, D; Yan, L, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giacinti, L | 1 |
| Giacinti, C | 1 |
| Gabellini, C | 1 |
| Rizzuto, E | 1 |
| Lopez, M | 1 |
| Giordano, A | 1 |
| Keen, JC | 1 |
| Yan, L | 1 |
| Mack, KM | 1 |
| Pettit, C | 1 |
| Smith, D | 1 |
| Sharma, D | 1 |
| Davidson, NE | 1 |
2 other studies available for scriptaid and Breast Cancer
| Article | Year |
|---|---|
Scriptaid effects on breast cancer cell lines.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Estr | 2012 |
A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine.
Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Division; Decitabi | 2003 |