scorpion-toxin-i--androctonus has been researched along with Prostatic-Neoplasms* in 1 studies
1 other study(ies) available for scorpion-toxin-i--androctonus and Prostatic-Neoplasms
Article | Year |
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AaHIV a sodium channel scorpion toxin inhibits the proliferation of DU145 prostate cancer cells.
Prostate cancer is the most highly diagnosed cancer in men worldwide. It is characterized by high proliferation, great invasion and metastatic potential. Sodium channel subtypes have been identified as highly expressed in different prostate cancer cell lines. In this study, we have screened the negatively charged fractions of Androctonus australis (Aa) scorpion venom to identify active peptides on DU145 prostate cancer cells proliferation. The most active compound was identified to be the sodium channel peptide AaHIV with an IC Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Humans; Male; NAV1.6 Voltage-Gated Sodium Channel; Prostatic Neoplasms; Scorpion Venoms; Scorpions; Sodium Channels | 2020 |