sclerotiorin has been researched along with Liver-Neoplasms* in 1 studies
1 other study(ies) available for sclerotiorin and Liver-Neoplasms
| Article | Year |
|---|---|
Semisynthesis and biological evaluation of (+)-sclerotiorin derivatives as antitumor agents for the treatment of hepatocellular carcinoma.
Hepatocellular carcinoma is one of the most common primary hepatic malignancy. Herein, a series of semisynthesized derivatives (2-30) of the natural product (+)-sclerotiorin (1) was prepared and evaluated the cytotoxic activities against six cancer cell lines. Among them, 3 and 5 were the most effective compounds against human hepatocellular carcinoma Bel-7402 cell line with IC Topics: Animals; Antineoplastic Agents; Apoptosis; Benzopyrans; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Humans; Liver Neoplasms; Mice; Xenograft Model Antitumor Assays | 2022 |