sclareolide and Neoplasms

sclareolide has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for sclareolide and Neoplasms

ArticleYear
Synthesis and biological activity of (+)-hedychilactone A and its analogs from (+)-sclareolide.
    Bioorganic & medicinal chemistry letters, 2006, Mar-15, Volume: 16, Issue:6

    Natural product hedychilactone A (3) has been synthesized from (+)-sclareolide by an efficient route. Two of the synthetic intermediates, 10 and 12, have shown strong growth inhibition effects against five cancer cell lines, human umbilical vein endothelial cell (HUVEC) and nitric oxide (NO) production. In particular, compound 15 showed selective inhibition activity against HUVEC growth without any cytotoxicity among tested cancer cell lines.

    Topics: Angiogenesis Inhibitors; Cells, Cultured; Diterpenes; Endothelium, Vascular; Humans; Neoplasms; Neovascularization, Physiologic; Nitric Oxide; Umbilical Veins

2006