Compounds > sclareol
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sclareol and Colonic Neoplasms

sclareol has been researched along with Colonic Neoplasms in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Assani, I; Chen, L; Du, Y; Feng, Y; Hou, PL; Huang, RZ; Li, Y; Liao, ZX; Liu, LF; Sun, B; Wang, CG; Zhao, SF1
Alevizopoulos, K; Demetzos, C; Dimas, K; Han, Z; Mahaira, LG; Pantazis, P; Sakellaridis, N; Tsimplouli, C1
Demetzos, C; Dimas, K; Georgopoulos, A; Hatziantoniou, S; Sotiriadou, N1
Alevizopoulos, K; Demetzos, C; Dimas, K; Georgopoulos, A; Hatziantoniou, S; Khan, H; Pantazis, P; Tseleni, S; Wyche, JH1

Other Studies

4 other study(ies) available for sclareol and Colonic Neoplasms

ArticleYear
Anti-proliferative effects of diterpenoids from
    Food & function, 2020, Sep-23, Volume: 11, Issue:9

    Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Shape; Colonic Neoplasms; Diterpenes; Gene Expression Regulation; HCT116 Cells; Humans; I-kappa B Kinase; Membrane Potential, Mitochondrial; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Plant Tubers; Sagittaria; Signal Transduction; Transcription Factor RelA

2020
The labdane diterpene sclareol (labd-14-ene-8, 13-diol) induces apoptosis in human tumor cell lines and suppression of tumor growth in vivo via a p53-independent mechanism of action.
    European journal of pharmacology, 2011, Volume: 666, Issue:1-3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Proliferation; Colonic Neoplasms; Cyclic AMP; Cyclin-Dependent Kinase Inhibitor p21; Diterpenes; DNA Damage; Enzyme Activation; G1 Phase; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Intracellular Space; Liposomes; Male; Mice; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2011
Cytotoxic and antitumor activity of liposome-incorporated sclareol against cancer cell lines and human colon cancer xenografts.
    Pharmacological research, 2006, Volume: 53, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cistus; Colonic Neoplasms; Diterpenes; HCT116 Cells; Humans; Liposomes; Male; Mice; Phytotherapy; Resins, Plant; Xenograft Model Antitumor Assays

2006
Sclareol induces apoptosis in human HCT116 colon cancer cells in vitro and suppression of HCT116 tumor growth in immunodeficient mice.
    Apoptosis : an international journal on programmed cell death, 2007, Volume: 12, Issue:4

    Topics: Animals; Apoptosis; Biomarkers; Caspases; Cell Cycle; Colonic Neoplasms; Diterpenes; DNA Damage; Enzyme Activation; HCT116 Cells; Humans; Mice; Mice, SCID

2007