schizandrin b has been researched along with Acute Liver Injury, Drug-Induced in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, Y; Cheng, L; Gao, Z; Wang, L; Wang, T; Wu, W; Zhang, Q | 1 |
| Pu, P; Shi, H; Tang, H; Yan, Y; Yang, H | 1 |
| Bai, HY; Feng, S | 1 |
| Feng, S; Liu, K; Qiu, B; Xu, X; Zhu, H; Zou, L | 1 |
| Chen, H; Hu, JP; Li, Y; Sheng, L; Wang, BL | 1 |
| Jia, ZH; Ko, KM; Pan, SY; Sun, N; Wang, XY; Yu, Q; Yu, ZL; Zhang, Y; Zhu, PL | 1 |
| Chen, Y; Li, L; Xin, Y; Xing, G; Zhang, T; Zhou, L | 1 |
| Chu, ZS; Ko, KM; Pan, SY; Sun, N; Wang, XY; Yu, ZL; Zhang, Y; Zhou, SF; Zhu, PL | 1 |
| Deng, Y; Feng, S; Liu, W; Xu, B; Xu, Z; Yang, T | 1 |
| Bi, H; Chen, P; Fan, X; Huang, M; Jiang, Y; Tan, H; Wang, Y; Zeng, H | 1 |
| He, ZX; Hu, C; Jin, H; Ko, KM; Pan, SY; Yang, T; Yu, ZL; Zhang, X; Zhang, Y; Zhou, SF; Zhou, ZW | 1 |
| Du, X; Gao, Z; Li, L; Li, Q; Shen, L; Zhang, J; Zhao, Z; Zou, Y | 1 |
| Chang, CY; Chen, JR; Chen, YL; Huang, CC; Huang, GC; Li, JS; Tsi, D; Yang, SC | 1 |
| Lavazza, A; Li Volti, G; Rezzani, R; Rodella, LF; Stacchiotti, A | 1 |
| Che, CT; Chen, Y; Ip, SP; Ko, KM; Lai, PB; Mao, QQ; Ng, EW; Poon, TC; Xian, YF | 1 |
| Chiu, PY; Ko, KM; Mak, DH; Poon, MK | 1 |
| Chiu, PY; Ko, KM; Leung, HY; Mak, DH; Poon, MK | 1 |
| Che, CT; Ip, SP; Ko, KM; Ma, CY | 1 |
| Ko, KM; Mak, DH | 1 |
| Che, CT; Ip, SP; Ko, KM | 1 |
| Ip, SP; Ko, KM; Yiu, HY | 1 |
| Liu, GT | 2 |
1 review(s) available for schizandrin b and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
[Biochemical and pharmacologic effects of wuweizi (Schizandra chinensis (Turcz.) Baill.) and its chemical contents on animal livers].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 Enzyme System; Drugs, Chinese Herbal; Lignans; Liver; Mitochondria, Liver; Polycyclic Compounds | 1988 |
22 other study(ies) available for schizandrin b and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Study on the Protective Effect of Schizandrin B against Acetaminophen-Induced Cytotoxicity in Human Hepatocyte.
Topics: Acetaminophen; Apoptosis Regulatory Proteins; Chemical and Drug Induced Liver Injury; Cyclooctanes; Hepatocytes; Humans; Lignans; Mitogen-Activated Protein Kinase Kinases; Polycyclic Compounds | 2022 |
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cyclooctanes; Diet; Doxorubicin; Ferroptosis; Lignans; Lipid Peroxidation; Oxidative Stress; Polycyclic Compounds; Rats | 2022 |
[Protection effects of schizandrin B against liver injury induced by clozapine in mice].
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Clozapine; Cyclooctanes; Glutathione; Heme Oxygenase-1; Lignans; Liver; Malondialdehyde; Membrane Proteins; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Polycyclic Compounds; Protective Agents; Signal Transduction; Superoxide Dismutase | 2017 |
Schisandrin B elicits the Keap1-Nrf2 defense system via carbene reactive metabolite which is less harmful to mice liver.
Topics: Activation, Metabolic; Animals; Cell Survival; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 Enzyme System; Hep G2 Cells; Humans; Kelch-Like ECH-Associated Protein 1; Lignans; Liver; Male; Methane; Mice; Microsomes, Liver; NF-E2-Related Factor 2; Polycyclic Compounds; Signal Transduction | 2018 |
Chemical-pharmacokinetic-pharmacodynamic fingerprints of Schisandra chinensis alcoholic extract.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cyclooctanes; Drugs, Chinese Herbal; Lignans; Male; Microsomes, Liver; Plants, Medicinal; Polycyclic Compounds; Random Allocation; Rats; Rats, Sprague-Dawley; Schisandra; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2013 |
Novel mouse model of combined hyperlipidemia associated with steatosis and liver injury by a single-dose intragastric administration of schisandrin B/cholesterol/bile salts mixture.
Topics: Administration, Oral; Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholesterol; Cyclooctanes; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Liver; Fenofibrate; Hyperlipidemias; Lignans; Lipoproteins; Male; Mice; Mice, Inbred ICR; Polycyclic Compounds; Time Factors; Triglycerides | 2013 |
Schisandrin B attenuates acetaminophen-induced hepatic injury through heat-shock protein 27 and 70 in mice.
Topics: Acetaminophen; Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Lignans; Liver; Male; Mice; Phytotherapy; Polycyclic Compounds; Schisandra; Time Factors | 2014 |
Time and dose relationships between schisandrin B- and schisandrae fructus oil-induced hepatotoxicity and the associated elevations in hepatic and serum triglyceride levels in mice.
Topics: Administration, Oral; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dose-Response Relationship, Drug; Lignans; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Molecular Structure; Plant Oils; Polycyclic Compounds; Schisandra; Time Factors; Triglycerides | 2014 |
Antioxidative effects of schidandrin B and green tea polyphenols against mercuric chloride-induced hepatotoxicity in rats.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cyclooctanes; Lignans; Liver; Mercuric Chloride; Oxidative Stress; Polycyclic Compounds; Polyphenols; Random Allocation; Rats; Rats, Wistar; Tea | 2014 |
Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Dioxoles; Lignans; Liver; Male; Membrane Proteins; Mice, Inbred C57BL; Polycyclic Compounds; Protective Agents; Schisandra | 2015 |
Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity.
Topics: Animals; Apoptosis; Autophagy; Cell Cycle; Cell Division; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cyclooctanes; G1 Phase; Hepatocytes; Lignans; Macrophages; Mice; Mitochondria, Liver; Polycyclic Compounds; S Phase; Signal Transduction | 2015 |
Heat shock proteins 27 and 70 contribute to the protection of Schisandrin B against d-galactosamine-induced liver injury in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cyclooctanes; Galactosamine; Gene Expression; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Lignans; Liver; Male; Mice; Mice, Inbred ICR; Polycyclic Compounds; Protective Agents; Quercetin; Schisandra | 2016 |
Effect of schisandrin B and sesamin mixture on CCl(4)-induced hepatic oxidative stress in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Drug Combinations; Drugs, Chinese Herbal; Glutathione; Glutathione Peroxidase; Lignans; Liver; Liver Diseases; Male; Oxidative Stress; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Silymarin; Superoxide Dismutase | 2009 |
Schisandrin B stimulates a cytoprotective response in rat liver exposed to mercuric chloride.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytoprotection; Heat-Shock Proteins; Lignans; Male; Mercuric Chloride; Polycyclic Compounds; Rats; Rats, Wistar | 2009 |
A proteomic approach in investigating the hepatoprotective mechanism of Schisandrin B: role of raf kinase inhibitor protein.
Topics: Animals; Apoptosis; Blotting, Western; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Electrophoresis, Gel, Two-Dimensional; Extracellular Signal-Regulated MAP Kinases; Lignans; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred BALB C; Phosphatidylethanolamine Binding Protein; Polycyclic Compounds; Protective Agents; Proteins; Proteome; Proteomics; Proto-Oncogene Proteins c-raf; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Statistics, Nonparametric | 2011 |
In vivo antioxidant action of a lignan-enriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin.
Topics: Alanine Transaminase; alpha-Tocopherol; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Emodin; Female; Fruit; Glutathione; L-Iditol 2-Dehydrogenase; Lignans; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Phytotherapy; Plant Extracts; Plant Roots; Polycyclic Compounds; Polygonum; Random Allocation; Schisandra | 2002 |
Effects of schisandrin B enantiomers on cellular glutathione and menadione toxicity in AML12 hepatocytes.
Topics: Animals; Cell Line; Chemical and Drug Induced Liver Injury; Cyclooctanes; Glutamate-Cysteine Ligase; Glutathione; Glutathione Reductase; Hepatocytes; L-Lactate Dehydrogenase; Lignans; Mice; Polycyclic Compounds; Vitamin K 3 | 2006 |
Methylenedioxy group as determinant of schisandrin in enhancing hepatic mitochondrial glutathione in carbon tetrachloride-intoxicated mice.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Drugs, Chinese Herbal; Female; Glutathione; Lignans; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Polycyclic Compounds; Structure-Activity Relationship | 1997 |
Alterations in susceptibility to carbon tetrachloride toxicity and hepatic antioxidant/detoxification system in streptozotocin-induced short-term diabetic rats: effects of insulin and Schisandrin B treatment.
Topics: Alanine Transaminase; Animals; Antioxidants; Blood Glucose; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Diabetes Mellitus, Experimental; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Insulin; Lignans; Liver; Liver Diseases; Male; Microsomes; Mitochondria, Liver; Oxidation-Reduction; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Streptozocin | 1997 |
Structure-activity relationship of schisandrins in enhancing liver mitochondrial glutathione status in CCl4-poisoned mice.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Female; Glutathione; Glutathione Reductase; Lignans; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Polycyclic Compounds; Structure-Activity Relationship | 1998 |
Differential effect of schisandrin B and dimethyl diphenyl bicarboxylate (DDB) on hepatic mitochondrial glutathione redox status in carbon tetrachloride intoxicated mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cyclooctanes; Female; Glutathione; Glutathione Reductase; Hydrocarbons, Chlorinated; Insecticides; L-Iditol 2-Dehydrogenase; Lignans; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Polycyclic Compounds | 2000 |
Pharmacological actions and clinical use of fructus schizandrae.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; Drugs, Chinese Herbal; Hepatitis B; Humans; Lignans; Lipid Peroxidation; Mice; Microsomes, Liver; Polycyclic Compounds; Rats | 1989 |