sch-527123 has been researched along with Inflammation* in 1 studies
1 other study(ies) available for sch-527123 and Inflammation
Article | Year |
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Diaminocyclobutenediones as potent and orally bioavailable CXCR2 receptor antagonists: SAR in the phenolic amide region.
A series of potent and orally bioavailable 3,4-diaminocyclobutenediones with various amide modifications and substitution on the left side phenyl ring were prepared and found to show significant inhibitory activities towards both CXCR2 and CXCR1 receptors. Topics: Administration, Oral; Amides; Animals; Area Under Curve; Chemistry, Pharmaceutical; Cyclobutanes; Diamines; Drug Design; Humans; Inflammation; Kinetics; Models, Chemical; Phenol; Rats; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Structure-Activity Relationship | 2009 |