sch-48973 has been researched along with Poliomyelitis in 4 studies
Poliomyelitis: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Copelyn, J | 1 |
| Hincks, JR | 2 |
| Wilmshurst, JM | 1 |
| Petersen, W | 1 |
| Howard, W | 1 |
| Jallow, S | 1 |
| Moonsamy, S | 1 |
| Seakamela, L | 1 |
| Suchard, M | 1 |
| Collett, MS | 2 |
| Eley, B | 1 |
| Sutter, RW | 1 |
| Modlin, JF | 2 |
| Zaffran, M | 1 |
| Benschop, K | 1 |
| Duizer, E | 1 |
| van der Avoort, H | 1 |
| Rhoden, E | 1 |
| Liu, H | 1 |
| Oberste, MS | 1 |
| McKinlay, MA | 1 |
| Hartford, M | 1 |
| Buontempo, PJ | 1 |
| Cox, S | 1 |
| Wright-Minogue, J | 1 |
| DeMartino, JL | 1 |
| Skelton, AM | 1 |
| Ferrari, E | 1 |
| Albin, R | 1 |
| Rozhon, EJ | 1 |
| Girijavallabhan, V | 1 |
| O'Connell, JF | 1 |
1 trial available for sch-48973 and Poliomyelitis
| Article | Year |
|---|---|
Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model.
Topics: Adult; Antiviral Agents; Cohort Studies; Female; Humans; Male; Middle Aged; Phenyl Ethers; Poliomyel | 2017 |
3 other studies available for sch-48973 and Poliomyelitis
| Article | Year |
|---|---|
Clearance of Immunodeficiency-associated Vaccine-derived Poliovirus Infection With Pocapavir.
Topics: Agammaglobulinemia; Antiviral Agents; Drugs, Investigational; Feces; Genetic Diseases, X-Linked; Hum | 2020 |
Completing Polio Eradication: The Case for Antiviral Drugs.
Topics: Antiviral Agents; Humans; Phenyl Ethers; Poliomyelitis; Poliovirus Vaccine, Oral | 2017 |
SCH 48973: a potent, broad-spectrum, antienterovirus compound.
Topics: Animals; Antiviral Agents; Brain; Enterovirus; Enterovirus Infections; Halogenated Diphenyl Ethers; | 1997 |