sch-23390 and Depression--Postpartum

sch-23390 has been researched along with Depression--Postpartum* in 1 studies

Other Studies

1 other study(ies) available for sch-23390 and Depression--Postpartum

ArticleYear
[Selective D1-receptor antagonist SCH23390 decreases maternal reactions in rats upon acute and chronic injections in postpartum period].
    Eksperimental'naia i klinicheskaia farmakologiia, 2012, Volume: 75, Issue:8

    The influence of the D1-receptor antagonist SCH23390 on the maternal behavior of female rats has been studied. It is established that a comparatively high dose of the drug (acute injections) significantly decreases both the locomotor activity and manifestations of the parental care. Lower dosages do not affect the locomotor activity, but still suppress the maternal behavior (after both acute and chronic injections of SCH23390). The obtained results are discussed in terms of the analysis of the maternal motivation mechanisms and the development of the D1-induced postpartum depression.

    Topics: Animals; Behavior, Animal; Benzazepines; Depression, Postpartum; Drug Administration Schedule; Female; Humans; Injections, Intraperitoneal; Maternal Behavior; Motor Activity; Postpartum Period; Rats; Receptors, Dopamine D1

2012