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sch 16134 and Drug Withdrawal Symptoms

sch 16134 has been researched along with Drug Withdrawal Symptoms in 9 studies

quazepam: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"Within a double-blind, comparative study on the effects of the long-half-life benzodiazepine (BDZ), quazepam, and the short-half-life BDZ, triazolam, on clinical symptomatology, sleep and anxiety of 45 patients with insomnia based on a mild to moderate generalized anxiety disorder (GAD) (ICD-9 code: 307."9.07Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam). ( Anderer, P; Brandstätter, N; Frey, R; Grünberger, J; Klösch, G; Mandl, M; Saletu, B; Wetter, T; Zeitlhofer, J, 1994)
"Within a double-blind, comparative study on the effects of the long-half-life benzodiazepine (BDZ), quazepam, and the short-half-life BDZ, triazolam, on clinical symptomatology, sleep and anxiety of 45 patients with insomnia based on a mild to moderate generalized anxiety disorder (GAD) (ICD-9 code: 307."5.07Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam). ( Anderer, P; Brandstätter, N; Frey, R; Grünberger, J; Klösch, G; Mandl, M; Saletu, B; Wetter, T; Zeitlhofer, J, 1994)
"Sixty-five patients, affected by sleep disorders, were entered into the study."2.67Quazepam versus triazolam in patients with sleep disorders: a double-blind study. ( Altamura, AC; Gianetti, S; Mauri, MC; Pugnetti, L, 1993)
"Temazepam did not produce any behavioral side effects during either drug condition."2.66Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal. ( Bixler, EO; Jacoby, JA; Kales, A; Kales, JD; Soldatos, CR; Vela-Bueno, A, 1986)
"To assess pharmacodynamic and pharmacokinetic properties of acute, subchronic and withdrawn quazepam, a single-blind, longitudinal study was run in eight male, healthy young volunteers."1.28Longitudinal study on pharmacodynamics and pharmacokinetics of acute, steady-state and withdrawn quazepam. ( Kauert, G; Klausnitzer, W; Schaffler, K; Wauschkuhn, CH, 1989)
" Some loss of effectiveness was noted during long-term use of both doses of quazepam and, to a lesser extent, of flurazepam."1.26Quazepam and flurazepam: long-term use and extended withdrawal. ( Bixler, EO; Jacoby, J; Kales, A; Kales, JD; Soldatos, CR; Vela-Bueno, A, 1982)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kales, A5
Scharf, MB1
Bixler, EO4
Schweitzer, PK1
Jacoby, JA3
Soldatos, CR5
Tietz, EI1
Roth, T1
Zorick, FJ1
Piccione, P1
Kramer, M1
Vela-Bueno, A2
Jacoby, J1
Kales, JD4
Mauri, MC1
Gianetti, S1
Pugnetti, L1
Altamura, AC1
Saletu, B1
Anderer, P1
Brandstätter, N1
Frey, R1
Grünberger, J1
Klösch, G1
Mandl, M1
Wetter, T1
Zeitlhofer, J1
Schaffler, K1
Kauert, G1
Wauschkuhn, CH1
Klausnitzer, W1

Reviews

1 review available for sch 16134 and Drug Withdrawal Symptoms

ArticleYear
Rebound insomnia and elimination half-life: assessment of individual subject response.
    Journal of clinical pharmacology, 1985, Volume: 25, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, D

1985

Trials

5 trials available for sch 16134 and Drug Withdrawal Symptoms

ArticleYear
The acute effect of quazepam on the sleep of chronic insomniacs. A dose-response study.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:11

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Chronic Disease; Clinical Trials as Topic;

1981
Quazepam versus triazolam in patients with sleep disorders: a double-blind study.
    International journal of clinical pharmacology research, 1993, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Double-Blind Method; Female; Human

1993
Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam).
    Neuropsychobiology, 1994, Volume: 29, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Double-Blind Method; Female; Humans; Hypnotics

1994
Rebound insomnia and elimination half-life: assessment of individual subject response.
    Journal of clinical pharmacology, 1985, Volume: 25, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, D

1985
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
    Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:3

    Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Drug Evaluation; Half-L

1986

Other Studies

4 other studies available for sch 16134 and Drug Withdrawal Symptoms

ArticleYear
Dose-response studies of quazepam.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Female; Humans; Male;

1981
Quazepam and flurazepam: long-term use and extended withdrawal.
    Clinical pharmacology and therapeutics, 1982, Volume: 32, Issue:6

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Drug Evaluation; Flurazepam; Half-Life; Humans; Middle

1982
Longitudinal study on pharmacodynamics and pharmacokinetics of acute, steady-state and withdrawn quazepam.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Electrooculography; Flurazepam; Hemo

1989
Quazepam: sleep laboratory studies of effectiveness and withdrawal.
    Clinical neuropharmacology, 1985, Volume: 8 Suppl 1

    Topics: Anti-Anxiety Agents; Benzodiazepines; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders

1985