Page last updated: 2024-09-03

sc 58125 and Allodynia

sc 58125 has been researched along with Allodynia in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertenshaw, SR; Burton, EG; Carter, JS; Cogburn, JN; Collins, PW; Docter, S; Graneto, MJ; Gregory, SA; Isakson, PC; Koboldt, CM; Lee, LF; Malecha, JW; Miyashiro, JM; Penning, TD; Perkins, WE; Rogers, RS; Rogier, DJ; Seibert, K; Talley, JJ; Veenhuizen, AW; Yu, SS; Zhang, YY1
Bornemeier, DA; Chan, K; Connor, DT; Doubleday, R; Dyer, RD; Gilbertsen, RB; Guglietta, A; Roth, BD; Schrier, DJ; Sercel, AD; Song, Y; Sorenson, RJ; Unangst, PC1
Beylin, VG; Bornemeier, DA; Chan, K; Connor, DT; Doubleday, R; Dyer, RD; Gilbertsen, RB; Guglietta, A; Roth, BD; Schrier, DJ; Sercel, AD; Song, Y; Sorenson, RJ; Unangst, PC1
Ni, K; Peng, Y; Zang, T; Zhou, L; Zhou, X1
Kajiyama, S; Kawamoto, M; Kurita, S; Matsunaga, A; Shiraishi, S; Yasuda, T; Yuge, O1
Dirig, DM; Isakson, PC; Yaksh, TL1
Hu, D; Syriatowicz, JP; Tracey, DJ; Walker, JS1
Conway, CM; Dirig, DM; Isakson, PC; Luo, ZD; Svensson, C; Yaksh, TL1

Other Studies

8 other study(ies) available for sc 58125 and Allodynia

ArticleYear
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hyperalgesia; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Molecular Structure; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides

1997
Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
    Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Gastric Mucosa; Humans; Hyperalgesia; Isoenzymes; Male; Membrane Proteins; Mice; Oxazoles; Phenols; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Thiazoles

1999
Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
    Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Carrageenan; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Gastric Mucosa; Humans; Hyperalgesia; In Vitro Techniques; Isoenzymes; Male; Membrane Proteins; Mice; Phenols; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sheep; Stomach Ulcer; Structure-Activity Relationship; Thiadiazoles

1999
COX-2 contributed to the remifentanil-induced hyperalgesia related to ephrinB/EphB signaling.
    Neurological research, 2019, Volume: 41, Issue:6

    Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Ephrins; Hyperalgesia; Injections, Spinal; Mice; Pyrazoles; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord

2019
Intrathecally administered COX-2 but not COX-1 or COX-3 inhibitors attenuate streptozotocin-induced mechanical hyperalgesia in rats.
    European journal of pharmacology, 2007, Jan-05, Volume: 554, Issue:1

    Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dinoprostone; Hyperalgesia; Injections, Spinal; Male; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Streptozocin

2007
Effect of COX-1 and COX-2 inhibition on induction and maintenance of carrageenan-evoked thermal hyperalgesia in rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: Animals; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Repression; Hot Temperature; Hyperalgesia; Ibuprofen; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley

1998
Hyperalgesia due to nerve injury: role of prostaglandins.
    Neuroscience, 1999, Volume: 94, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Functional Laterality; Hindlimb; Hyperalgesia; Indomethacin; Male; Meloxicam; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Sciatic Nerve; Thiazines; Thiazoles; Time Factors

1999
The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Aug-15, Volume: 21, Issue:16

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Ibuprofen; Injections, Intraperitoneal; Injections, Spinal; Isoenzymes; Male; Membrane Proteins; N-Methylaspartate; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2001