sc 41661a has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 3 studies
*Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS. [MeSH]
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Anderson, KM; Harris, JE; Jajeh, A; Meng, J; Peng, J; Seed, TM | 1 |
Anderson, KM; Harris, JE; Jajeh, A; Levin, J; Seed, T | 1 |
Anderson, KM; Harris, JE; Jajeh, A; Meng, J; Plate, JM; Seed, T | 1 |
3 other study(ies) available for sc 41661a and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Article | Year |
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Morphologic changes of apoptosis induced in human chronic myelogenous leukemia "blast" cells by SC41661A (Searle), a selective inhibitor of 5-lipoxygenase.
Topics: Amides; Apoptosis; Cell Death; Cell Division; Chromatin; DNA Damage; DNA, Neoplasm; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lipoxygenase Inhibitors; Pyridines; Tumor Cells, Cultured | 1994 |
Induction of apoptosis in blood cells from a patient with acute myelogenous leukemia by SC41661A, a selective inhibitor of 5-lipoxygenase.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetamides; Amides; Apoptosis; Base Sequence; Blast Crisis; Blood Cells; Codon; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lipoxygenase Inhibitors; Microscopy, Electron; Molecular Sequence Data; Oligonucleotides, Antisense; Phenyl Ethers; Pyridines; RNA, Neoplasm; Thymidine; Tritium | 1993 |
Selective inhibitors of 5-lipoxygenase reduce CML blast cell proliferation and induce limited differentiation and apoptosis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetamides; Amides; Antineoplastic Agents; Apoptosis; Blast Crisis; Cell Differentiation; Cell Division; DNA, Neoplasm; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lipoxygenase Inhibitors; Phenyl Ethers; Pyridines; Tumor Cells, Cultured | 1995 |