sb-742457 has been researched along with Cognitive-Dysfunction* in 1 studies
1 other study(ies) available for sb-742457 and Cognitive-Dysfunction
Article | Year |
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2-Aminoimidazole-based antagonists of the 5-HT
A new strategy in the design of aminergic GPCR ligands is proposed - the use of aromatic, heterocyclic basic moieties in place of the evergreen piperazine or alicyclic and aliphatic amines. This hypothesis has been tested using a benchmark series of 5-HT Topics: Animals; Cells, Cultured; Cognitive Dysfunction; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Hep G2 Cells; Humans; Imidazoles; Male; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Structure-Activity Relationship | 2019 |