sb-742457 and Cognitive-Dysfunction

sb-742457 has been researched along with Cognitive-Dysfunction* in 1 studies

Other Studies

1 other study(ies) available for sb-742457 and Cognitive-Dysfunction

Article	Year
2-Aminoimidazole-based antagonists of the 5-HT European journal of medicinal chemistry, 2019, Oct-01, Volume: 179 A new strategy in the design of aminergic GPCR ligands is proposed - the use of aromatic, heterocyclic basic moieties in place of the evergreen piperazine or alicyclic and aliphatic amines. This hypothesis has been tested using a benchmark series of 5-HT Topics: Animals; Cells, Cultured; Cognitive Dysfunction; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Hep G2 Cells; Humans; Imidazoles; Male; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Structure-Activity Relationship	2019

Article

Year

2-Aminoimidazole-based antagonists of the 5-HT

European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

A new strategy in the design of aminergic GPCR ligands is proposed - the use of aromatic, heterocyclic basic moieties in place of the evergreen piperazine or alicyclic and aliphatic amines. This hypothesis has been tested using a benchmark series of 5-HT

Topics: Animals; Cells, Cultured; Cognitive Dysfunction; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Hep G2 Cells; Humans; Imidazoles; Male; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Structure-Activity Relationship

2019