sb-525334 and Vascular-Malformations

sb-525334 has been researched along with Vascular-Malformations* in 1 studies

Other Studies

1 other study(ies) available for sb-525334 and Vascular-Malformations

Article	Year
Activation of Ras in the Vascular Endothelium Induces Brain Vascular Malformations and Hemorrhagic Stroke. Cell reports, 2018, 09-11, Volume: 24, Issue:11 Cerebrovascular malformations (CVMs) affect approximately 3% of the population, risking hemorrhagic stroke, seizures, and neurological deficits. Recently Ras mutations have been identified in a majority of brain arterio-venous malformations. We generated an endothelial-specific, inducible HRAS Topics: Activin Receptors, Type II; Animals; Brain; Cells, Cultured; Endothelial Cells; Female; Fluorescent Antibody Technique; Imidazoles; Immunohistochemistry; Male; Mice; Mice, Transgenic; Pericytes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta; Vascular Malformations	2018

Article

Year

Activation of Ras in the Vascular Endothelium Induces Brain Vascular Malformations and Hemorrhagic Stroke.

Cell reports, 2018, 09-11, Volume: 24, Issue:11

Cerebrovascular malformations (CVMs) affect approximately 3% of the population, risking hemorrhagic stroke, seizures, and neurological deficits. Recently Ras mutations have been identified in a majority of brain arterio-venous malformations. We generated an endothelial-specific, inducible HRAS

Topics: Activin Receptors, Type II; Animals; Brain; Cells, Cultured; Endothelial Cells; Female; Fluorescent Antibody Technique; Imidazoles; Immunohistochemistry; Male; Mice; Mice, Transgenic; Pericytes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta; Vascular Malformations

2018