sb 239063 has been researched along with Pneumonia in 1 studies
SB 239063: structure in first source
SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.
Pneumonia: Infection of the lung often accompanied by inflammation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, SJ | 1 |
| Fenwick, PS | 1 |
| Nicholson, AG | 1 |
| Kirschenbaum, F | 1 |
| Finney-Hayward, TK | 1 |
| Higgins, LS | 1 |
| Giembycz, MA | 1 |
| Barnes, PJ | 1 |
| Donnelly, LE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Regulation of the Release of Inflammatory Mediators From Lung Macrophages.[NCT00147017] | 17 participants (Actual) | Observational | 2001-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00147017)
Timeframe: 20 hours
| Intervention | ng/ml (Mean) |
|---|---|
| Smokers | 220.8 |
| Ex-smokers | 251.2 |
| Emphysema Lung Transplant | 167.8 |
GM-CSF, granulocyte macrophage-colony stimulating factor (NCT00147017)
Timeframe: 20 hours
| Intervention | ng/ml (Mean) |
|---|---|
| Smokers | 2.2 |
| Ex-smokers | 1.8 |
| Emphysema Lung Transplant | 2.6 |
measure release of inflammatory mediators from isolated macrophages (NCT00147017)
Timeframe: 20 hours
| Intervention | ng/ml (Mean) |
|---|---|
| Smokers | 6.1 |
| Ex-smokers | 3.8 |
| Emphysema Lung Transplant | 2.6 |
1 other study available for sb 239063 and Pneumonia
| Article | Year |
|---|---|
Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages.
Topics: Blotting, Western; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Female; Granulocyte | 2006 |