Page last updated: 2024-11-04

sb 239063 and Myocardial Ischemia

sb 239063 has been researched along with Myocardial Ischemia in 1 studies

SB 239063: structure in first source
SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"Adult male rats were subjected to 30 min ischemia and 4 (apoptosis assay) or 24 h (myocardial infarction determination) of reperfusion and treated with vehicle, SB 239063, insulin or insulin plus wortmannin."3.72Early anti-apoptosis treatment reduces myocardial infarct size after a prolonged reperfusion. ( Christopher, TA; Gao, E; Gao, F; Liu, HR; Lopez, BL; Ma, XL; Tao, L; Yan, W, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F1
Tao, L1
Yan, W1
Gao, E1
Liu, HR1
Lopez, BL1
Christopher, TA1
Ma, XL1

Other Studies

1 other study available for sb 239063 and Myocardial Ischemia

ArticleYear
Early anti-apoptosis treatment reduces myocardial infarct size after a prolonged reperfusion.
    Apoptosis : an international journal on programmed cell death, 2004, Volume: 9, Issue:5

    Topics: Androstadienes; Animals; Apoptosis; Disease Models, Animal; Imidazoles; Insulin; Male; Myocardial In

2004