sb 239063 has been researched along with Ischemic Attack, Transient in 2 studies
SB 239063: structure in first source
SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| " dosing regimen that provided effective plasma concentrations of 0." | 1.31 | SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia. ( Adams, JL; Badger, AM; Barone, FC; Erhardt, JA; Hunter, AJ; Irving, EA; Kassis, S; Kumar, S; Lee, JC; Legos, JJ; McVey, MJ; Nelson, AH; Ohlstein, EH; Parsons, AA; Ray, AM; Smith, BR; Ward, K; White, RF, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barone, FC | 2 |
| Irving, EA | 1 |
| Ray, AM | 1 |
| Lee, JC | 1 |
| Kassis, S | 1 |
| Kumar, S | 1 |
| Badger, AM | 1 |
| White, RF | 2 |
| McVey, MJ | 1 |
| Legos, JJ | 2 |
| Erhardt, JA | 2 |
| Nelson, AH | 1 |
| Ohlstein, EH | 1 |
| Hunter, AJ | 1 |
| Ward, K | 1 |
| Smith, BR | 1 |
| Adams, JL | 1 |
| Parsons, AA | 2 |
| Lenhard, SC | 1 |
| Chandra, S | 1 |
| Tuma, RF | 1 |
2 other studies available for sb 239063 and Ischemic Attack, Transient
| Article | Year |
|---|---|
SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Brain; Cerebrovascular Circulati | 2001 |
SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia.
Topics: Animals; Cell Death; Cerebral Infarction; Enzyme Inhibitors; Imidazoles; Ischemic Attack, Transient; | 2001 |