Page last updated: 2024-11-04

sb 239063 and Hypertension, Pulmonary

sb 239063 has been researched along with Hypertension, Pulmonary in 1 studies

SB 239063: structure in first source
SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
"In a bleomycin-induced pulmonary fibrosis model in rats, treatment with SB 239063 (2."1.31SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung. ( Adams, JL; Bochnowicz, S; Griswold, DE; Hay, DW; Lee, JC; Osborn, RR; Rieman, DJ; Romanic, AM; Underwood, DC; Webb, EF, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Underwood, DC1
Osborn, RR1
Bochnowicz, S1
Webb, EF1
Rieman, DJ1
Lee, JC1
Romanic, AM1
Adams, JL1
Hay, DW1
Griswold, DE1

Other Studies

1 other study available for sb 239063 and Hypertension, Pulmonary

ArticleYear
SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:5

    Topics: Animals; Bleomycin; Cells, Cultured; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Guinea Pi

2000