sb 239063 has been researched along with Bronchial Hyperreactivity in 2 studies
SB 239063: structure in first source
SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bronchial asthma is a chronic inflammatory disorder of the airway accompanied by increased vascular permeability." | 1.38 | Inhibition of p38 MAPK reduces expression of vascular endothelial growth factor in allergic airway disease. ( Jeon, MS; Kim, SR; Lee, KS; Lee, YC; Park, SJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SR | 2 |
| Lee, KS | 2 |
| Park, SJ | 2 |
| Min, KH | 1 |
| Lee, MH | 1 |
| Lee, KA | 1 |
| Bartov, O | 1 |
| Atlas, D | 1 |
| Lee, YC | 2 |
| Jeon, MS | 1 |
2 other studies available for sb 239063 and Bronchial Hyperreactivity
| Article | Year |
|---|---|
A novel dithiol amide CB3 attenuates allergic airway disease through negative regulation of p38 mitogen-activated protein kinase.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dis | 2011 |
Inhibition of p38 MAPK reduces expression of vascular endothelial growth factor in allergic airway disease.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Dise | 2012 |