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sb 239063 and Brain Ischemia

sb 239063 has been researched along with Brain Ischemia in 2 studies

SB 239063: structure in first source
SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"SB 239063 was administered orally pre- and post-stroke and intravenously post-stroke."2.41Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia. ( Adams, JL; Badger, AM; Barone, FC; Erhardt, JA; Harrison, DC; Hunter, AJ; Irving, EA; Kassis, S; Kumar, S; Lee, JC; Legos, JJ; Ohlstein, EH; Parsons, AA; Philpott, K; Ray, AM; Smith, BR, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wallace, BK1
Jelks, KA1
O'Donnell, ME1
Barone, FC1
Irving, EA1
Ray, AM1
Lee, JC1
Kassis, S1
Kumar, S1
Badger, AM1
Legos, JJ1
Erhardt, JA1
Ohlstein, EH1
Hunter, AJ1
Harrison, DC1
Philpott, K1
Smith, BR1
Adams, JL1
Parsons, AA1

Reviews

1 review available for sb 239063 and Brain Ischemia

ArticleYear
Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia.
    Medicinal research reviews, 2001, Volume: 21, Issue:2

    Topics: Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Humans; Imidazoles; Interleukin-1; Mitoge

2001

Other Studies

1 other study available for sb 239063 and Brain Ischemia

ArticleYear
Ischemia-induced stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransport involves p38 and JNK MAP kinases.
    American journal of physiology. Cell physiology, 2012, Feb-01, Volume: 302, Issue:3

    Topics: Animals; Anthracenes; Blood-Brain Barrier; Brain; Brain Ischemia; Bumetanide; Cattle; Cell Hypoxia;

2012