sb 239063 has been researched along with Brain Ischemia in 2 studies
SB 239063: structure in first source
SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "SB 239063 was administered orally pre- and post-stroke and intravenously post-stroke." | 2.41 | Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia. ( Adams, JL; Badger, AM; Barone, FC; Erhardt, JA; Harrison, DC; Hunter, AJ; Irving, EA; Kassis, S; Kumar, S; Lee, JC; Legos, JJ; Ohlstein, EH; Parsons, AA; Philpott, K; Ray, AM; Smith, BR, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wallace, BK | 1 |
| Jelks, KA | 1 |
| O'Donnell, ME | 1 |
| Barone, FC | 1 |
| Irving, EA | 1 |
| Ray, AM | 1 |
| Lee, JC | 1 |
| Kassis, S | 1 |
| Kumar, S | 1 |
| Badger, AM | 1 |
| Legos, JJ | 1 |
| Erhardt, JA | 1 |
| Ohlstein, EH | 1 |
| Hunter, AJ | 1 |
| Harrison, DC | 1 |
| Philpott, K | 1 |
| Smith, BR | 1 |
| Adams, JL | 1 |
| Parsons, AA | 1 |
1 review available for sb 239063 and Brain Ischemia
| Article | Year |
|---|---|
Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia.
Topics: Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Humans; Imidazoles; Interleukin-1; Mitoge | 2001 |
1 other study available for sb 239063 and Brain Ischemia
| Article | Year |
|---|---|
Ischemia-induced stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransport involves p38 and JNK MAP kinases.
Topics: Animals; Anthracenes; Blood-Brain Barrier; Brain; Brain Ischemia; Bumetanide; Cattle; Cell Hypoxia; | 2012 |