sb 239063 has been researched along with Asthma in 3 studies
SB 239063: structure in first source
SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ozone exposure worsens the development of allergen-induced asthma." | 7.79 | Activation of p38 mitogen-activated protein kinase in ovalbumin and ozone-induced mouse model of asthma. ( Bao, A; Chung, KF; Li, F; Liang, L; Zhang, M; Zhou, X, 2013) |
| "Ozone exposure worsens the development of allergen-induced asthma." | 3.79 | Activation of p38 mitogen-activated protein kinase in ovalbumin and ozone-induced mouse model of asthma. ( Bao, A; Chung, KF; Li, F; Liang, L; Zhang, M; Zhou, X, 2013) |
| "Bronchial asthma is a chronic inflammatory disorder of the airway accompanied by increased vascular permeability." | 1.38 | Inhibition of p38 MAPK reduces expression of vascular endothelial growth factor in allergic airway disease. ( Jeon, MS; Kim, SR; Lee, KS; Lee, YC; Park, SJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, L | 1 |
| Li, F | 1 |
| Bao, A | 1 |
| Zhang, M | 1 |
| Chung, KF | 1 |
| Zhou, X | 1 |
| Kim, SR | 2 |
| Lee, KS | 2 |
| Park, SJ | 2 |
| Min, KH | 1 |
| Lee, MH | 1 |
| Lee, KA | 1 |
| Bartov, O | 1 |
| Atlas, D | 1 |
| Lee, YC | 2 |
| Jeon, MS | 1 |
3 other studies available for sb 239063 and Asthma
| Article | Year |
|---|---|
Activation of p38 mitogen-activated protein kinase in ovalbumin and ozone-induced mouse model of asthma.
Topics: Adrenal Cortex Hormones; Animals; Asthma; Disease Models, Animal; Drug Therapy, Combination; Dual Sp | 2013 |
A novel dithiol amide CB3 attenuates allergic airway disease through negative regulation of p38 mitogen-activated protein kinase.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dis | 2011 |
Inhibition of p38 MAPK reduces expression of vascular endothelial growth factor in allergic airway disease.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Dise | 2012 |