sb 239063 has been researched along with Apoplexy in 4 studies
SB 239063: structure in first source
SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Numerous pathological mediators of cardiac hypertrophy (eg, neurohormones, cytokines, and stretch) have been shown to activate p38 MAPK." | 1.31 | Hypertensive end-organ damage and premature mortality are p38 mitogen-activated protein kinase-dependent in a rat model of cardiac hypertrophy and dysfunction. ( Adams, JL; Angermann, CE; Behr, TM; Brooks, DP; Chandra, S; Coatney, RW; Kumar, S; Lee, JC; Nelson, AH; Nerurkar, SS; Ohlstein, EH; Sackner-Bernstein, JD; Sisko, J; Sulpizio, A; Willette, RN; Woods, TN, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wallace, BK | 1 |
| Jelks, KA | 1 |
| O'Donnell, ME | 1 |
| Lenhard, SC | 1 |
| Nerurkar, SS | 2 |
| Schaeffer, TR | 1 |
| Mirabile, RC | 1 |
| Boyce, RW | 1 |
| Adams, DF | 1 |
| Jucker, BM | 1 |
| Willette, RN | 2 |
| Barone, FC | 1 |
| Parsons, AA | 1 |
| Behr, TM | 1 |
| Nelson, AH | 1 |
| Coatney, RW | 1 |
| Woods, TN | 1 |
| Sulpizio, A | 1 |
| Chandra, S | 1 |
| Brooks, DP | 1 |
| Kumar, S | 1 |
| Lee, JC | 1 |
| Ohlstein, EH | 1 |
| Angermann, CE | 1 |
| Adams, JL | 1 |
| Sisko, J | 1 |
| Sackner-Bernstein, JD | 1 |
1 review available for sb 239063 and Apoplexy
| Article | Year |
|---|---|
Therapeutic potential of anti-inflammatory drugs in focal stroke.
Topics: Animals; Anti-Inflammatory Agents; Brain Injuries; Cell Adhesion Molecules; Cytokines; Gene Expressi | 2000 |
3 other studies available for sb 239063 and Apoplexy
| Article | Year |
|---|---|
Ischemia-induced stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransport involves p38 and JNK MAP kinases.
Topics: Animals; Anthracenes; Blood-Brain Barrier; Brain; Brain Ischemia; Bumetanide; Cattle; Cell Hypoxia; | 2012 |
p38 MAPK inhibitors ameliorate target organ damage in hypertension: Part 2. Improved renal function as assessed by dynamic contrast-enhanced magnetic resonance imaging.
Topics: Albuminuria; Animals; Contrast Media; Creatinine; Dietary Fats; Endothelium, Vascular; Enzyme Inhibi | 2003 |
Hypertensive end-organ damage and premature mortality are p38 mitogen-activated protein kinase-dependent in a rat model of cardiac hypertrophy and dysfunction.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; E | 2001 |