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sb 216995 and Arthritis

sb 216995 has been researched along with Arthritis in 1 studies

Arthritis: Acute or chronic inflammation of JOINTS.

Research Excerpts

ExcerptRelevanceReference
" One of the compounds, 9 (SB 210313) which lacked measureable activity as an inhibitor of the enzymes of arachidonate metabolism, and had good potency in the binding and in vivo TNF inhibition assays, was tested for antiarthritic activity in the AA rat model of arthritis."3.691-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency. ( Adams, JL; Badger, AM; Boehm, JC; Bradbeer, J; Breton, JJ; Chabot-Fletcher, MC; Gallagher, TF; Garigipati, RS; Griswold, DE; Hillegass, LM; Laydon, JT; Lee, JC; Sheldrake, PL; Smietana, JM; Sorenson, ME, 1996)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boehm, JC1
Smietana, JM1
Sorenson, ME1
Garigipati, RS1
Gallagher, TF1
Sheldrake, PL1
Bradbeer, J1
Badger, AM1
Laydon, JT1
Lee, JC1
Hillegass, LM1
Griswold, DE1
Breton, JJ1
Chabot-Fletcher, MC1
Adams, JL1

Other Studies

1 other study available for sb 216995 and Arthritis

ArticleYear
1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.
    Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Art

1996