Page last updated: 2024-09-05

sb 216763 and Pancreatic Neoplasms

sb 216763 has been researched along with Pancreatic Neoplasms in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Billadeau, DD; Blond, SY; Gaisina, IN; Gallier, F; Guo, S; Holzle, D; Kim, KH; Kozikowski, AP; Kurome, T; Luchini, DN; Ougolkov, AV	1
Boucher, MJ; Cagnol, S; Marchand, B; Tremblay, I	1

Other Studies

2 other study(ies) available for sb 216763 and Pancreatic Neoplasms

Article	Year
From a natural product lead to the identification of potent and selective benzofuran-3-yl-(indol-3-yl)maleimides as glycogen synthase kinase 3beta inhibitors that suppress proliferation and survival of pancreatic cancer cells. Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7 Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase 2; Drug Screening Assays, Antitumor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Maleimides; Models, Molecular; Pancreatic Neoplasms; Structure-Activity Relationship; X-Linked Inhibitor of Apoptosis Protein	2009
Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms. Carcinogenesis, 2012, Volume: 33, Issue:3 Topics: Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glycogen Synthase Kinase 3; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; MAP Kinase Signaling System; Membrane Proteins; Pancreas; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; Receptors, Death Domain; RNA, Messenger	2012

Article

Year

From a natural product lead to the identification of potent and selective benzofuran-3-yl-(indol-3-yl)maleimides as glycogen synthase kinase 3beta inhibitors that suppress proliferation and survival of pancreatic cancer cells.

Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7

Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase 2; Drug Screening Assays, Antitumor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Maleimides; Models, Molecular; Pancreatic Neoplasms; Structure-Activity Relationship; X-Linked Inhibitor of Apoptosis Protein

2009

Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms.

Carcinogenesis, 2012, Volume: 33, Issue:3

Topics: Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glycogen Synthase Kinase 3; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; MAP Kinase Signaling System; Membrane Proteins; Pancreas; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; Receptors, Death Domain; RNA, Messenger

2012