sb 216763 has been researched along with Cardiovascular Stroke in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, X; Chang, C; Han, S; Komal, S; Ouyang, X; Su, X; Wang, S; Xu, L; Yao, Y; Zang, M; Zhang, L | 1 |
| Chen, J; Hu, W; Hu, X; Huang, J; Jiang, Z; Liu, X; Nan, J; Ni, C; Su, S; Wang, C; Wang, J; Wang, Y; Wu, R; Yang, F; Yu, H; Zeng, Z; Zhang, N; Zhao, J; Zhu, K; Zhu, W | 1 |
| Abbott, GW; Crump, SM; Hu, Z; Zhang, P | 1 |
| Berdeaux, A; Chenoune, M; Couvreur, N; Ghaleh, B; Pons, S; Tissier, R; Waintraub, X | 1 |
| Brink, PR; Glass, PS; Liu, L; Rebecchi, MJ; Zhu, J | 1 |
| Jeong, CW; Jeong, HJ; Kim, SJ; Lee, CS; Lee, SH; Yoo, KY | 1 |
| Sharma, PL; Singh, M; Yadav, HN | 1 |
| Cao, YY; Chen, QL; Fang, WP; Gu, EW; Zhang, L; Zhu, Y | 1 |
| Gross, ER; Gross, GJ; Hsu, AK | 3 |
| Altaf, E; Kaga, S; Maulik, N; Zhan, L | 1 |
| Assaly, R; Berdeaux, A; Dubois-Randé, JL; Morin, D; Obame, FN; Plin-Mercier, C; Zini, R | 1 |
| Mozaffari, MS; Schaffer, SW | 1 |
| Derumeaux, G; Gomez, L; Ovize, M; Paillard, M; Thibault, H | 1 |
15 other study(ies) available for sb 216763 and Cardiovascular Stroke
| Article | Year |
|---|---|
Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction.
Topics: Animals; CARD Signaling Adaptor Proteins; Enzyme Activation; Fibroblasts; Glycogen Synthase Kinase 3 beta; Indoles; Inflammasomes; Inflammation; Male; Maleimides; Myocardial Infarction; Myocardial Ischemia; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Protein Kinase Inhibitors; Protein Multimerization; Rats, Sprague-Dawley; Vascular Remodeling | 2020 |
Leptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation.
Topics: Animals; Glycogen Synthase Kinase 3; GTP Phosphohydrolases; Humans; Indoles; Leptin; Leupeptins; Male; Maleimides; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Metalloendopeptidases; Mice; Mitochondrial Proteins; Myocardial Infarction; Proteolysis; Signal Transduction; Ubiquitination | 2018 |
Kcne2 deletion attenuates acute post-ischaemia/reperfusion myocardial infarction.
Topics: Animals; Disease Models, Animal; Indoles; Ischemia; Maleimides; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphorylation; Potassium Channels, Voltage-Gated | 2016 |
The ceiling effect of pharmacological postconditioning with the phytoestrogen genistein is reversed by the GSK3beta inhibitor SB 216763 [3-(2,4-dichlorophenyl)-4(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione] through mitochondrial ATP-dependent potassium c
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Decanoic Acids; Estradiol; Genistein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart; Heart Rate; Hydroxy Acids; Indoles; Ischemic Preconditioning, Myocardial; KATP Channels; Male; Maleimides; Mitochondria; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Phosphorylation; Proto-Oncogene Proteins c-akt; Rabbits | 2009 |
Cardioprotection of the aged rat heart by GSK-3beta inhibitor is attenuated: age-related changes in mitochondrial permeability transition pore modulation.
Topics: Aging; Animals; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart; Indoles; Male; Maleimides; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; NAD; Rats; Rats, Inbred F344; Reactive Oxygen Species | 2011 |
Curcumin protects against regional myocardial ischemia/reperfusion injury through activation of RISK/GSK-3β and inhibition of p38 MAPK and JNK.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cardiotonic Agents; Curcumin; Drug Therapy, Combination; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Ventricles; Indoles; Male; Maleimides; MAP Kinase Signaling System; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley | 2012 |
Pharmacological inhibition of GSK-3β produces late phase of cardioprotection in hyperlipidemic rat: possible involvement of HSP 72.
Topics: Animals; Diet, High-Fat; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HSP72 Heat-Shock Proteins; Hyperlipidemias; Indoles; Ischemic Preconditioning, Myocardial; Male; Maleimides; Myocardial Infarction; Myocardium; Organ Culture Techniques; Oximes; Quercetin; Rats; Rats, Wistar; Reperfusion Injury | 2012 |
Diabetes mellitus abrogates the cardioprotection of sufentanil against ischaemia/reperfusion injury by altering glycogen synthase kinase-3β.
Topics: Anesthetics, Intravenous; Animals; Blood Pressure; Blotting, Western; Cardiotonic Agents; Diabetes Mellitus, Experimental; Electrocardiography; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Heart Rate; Indoles; Male; Maleimides; Myocardial Infarction; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sufentanil; Troponin I | 2013 |
Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts.
Topics: Aminophenols; Androstadienes; Animals; Benzamides; Cardiotonic Agents; Chromones; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Male; Maleimides; Morphine; Morpholines; Myocardial Infarction; Narcotic Antagonists; Nuclear Receptor Subfamily 1, Group F, Member 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Premedication; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Signal Transduction; Sirolimus; Wortmannin | 2004 |
Glycogen synthase kinase-3beta/beta-catenin promotes angiogenic and anti-apoptotic signaling through the induction of VEGF, Bcl-2 and survivin expression in rat ischemic preconditioned myocardium.
Topics: Animals; Apoptosis; beta Catenin; Cell Nucleus; Coronary Vessels; Cytosol; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Inhibitor of Apoptosis Proteins; Ischemic Preconditioning, Myocardial; Lithium; Lymphoid Enhancer-Binding Factor 1; Male; Maleimides; Microtubule-Associated Proteins; Myocardial Infarction; Neovascularization, Physiologic; Oncogene Protein v-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Repressor Proteins; Signal Transduction; Survivin; T Cell Transcription Factor 1; Vascular Endothelial Growth Factor A | 2006 |
GSK3beta inhibition and K(ATP) channel opening mediate acute opioid-induced cardioprotection at reperfusion.
Topics: Analgesics, Opioid; Androstadienes; Animals; Benzamides; Benzopyrans; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanidines; Heart Rate; Imidazoles; Indoles; Ion Channel Gating; Male; Maleimides; Morphine; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Sarcolemma; Signal Transduction; Time Factors; Wortmannin | 2007 |
Delayed cardioprotection afforded by the glycogen synthase kinase 3 inhibitor SB-216763 occurs via a KATP- and MPTP-dependent mechanism at reperfusion.
Topics: Animals; Atractyloside; Benzamides; Blood Gas Analysis; Blood Pressure; Cardiotonic Agents; Glycogen Synthase Kinase 3; Heart Rate; Indoles; KATP Channels; Male; Maleimides; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Ischemia; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley | 2008 |
Cardioprotective effect of morphine and a blocker of glycogen synthase kinase 3 beta, SB216763 [3-(2,4-dichlorophenyl)-4(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione], via inhibition of the mitochondrial permeability transition pore.
Topics: Animals; Cardiotonic Agents; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Intracellular Membranes; Male; Maleimides; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Morphine; Myocardial Infarction; Permeability; Rats; Rats, Wistar | 2008 |
Effect of pressure overload on cardioprotection of mitochondrial KATP channels and GSK-3beta: interaction with the MPT pore.
Topics: Animals; Cardiotonic Agents; Cyclosporine; Diazoxide; Disease Models, Animal; Glyburide; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hypertension; In Vitro Techniques; Indoles; Lithium Chloride; Male; Maleimides; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Ventricular Function, Left; Ventricular Pressure | 2008 |
Inhibition of GSK3beta by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion.
Topics: Animals; Cyclosporine; Disease Models, Animal; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Ischemic Preconditioning, Myocardial; Maleimides; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Phosphorylation; Phosphorylation | 2008 |