sb 206553 has been researched along with Muscle Contraction in 3 studies
SB 206553: a high-affinity 5-HT(2C/2B) antagonist; structure given in first source
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1 Tegaserod (Zelnorm) is a potent 5-hydroxytryptamine4 (5-HT4) receptor agonist with clinical efficacy in disorders associated with reduced gastrointestinal motility and transit." | 1.32 | The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo. ( Armstrong, SR; Beattie, DT; Humphrey, PP; Mai, N; Marquess, D; McCullough, JL; Pulido-Rios, T; Richardson, C; Sandlund, C; Smith, JA; Vickery, RG, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Audia, JE | 1 |
| Evrard, DA | 1 |
| Murdoch, GR | 1 |
| Droste, JJ | 1 |
| Nissen, JS | 1 |
| Schenck, KW | 1 |
| Fludzinski, P | 1 |
| Lucaites, VL | 1 |
| Nelson, DL | 1 |
| Cohen, ML | 1 |
| Beattie, DT | 1 |
| Smith, JA | 1 |
| Marquess, D | 1 |
| Vickery, RG | 1 |
| Armstrong, SR | 1 |
| Pulido-Rios, T | 1 |
| McCullough, JL | 1 |
| Sandlund, C | 1 |
| Richardson, C | 1 |
| Mai, N | 1 |
| Humphrey, PP | 1 |
| Javid, FA | 1 |
| Naylor, RJ | 1 |
3 other studies available for sb 206553 and Muscle Contraction
| Article | Year |
|---|---|
Potent, selective tetrahydro-beta-carboline antagonists of the serotonin 2B (5HT2B) contractile receptor in the rat stomach fundus.
Topics: Animals; Carbolines; Cell Line; Cricetinae; Gastric Fundus; In Vitro Techniques; Male; Mesocricetus; | 1996 |
The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo.
Topics: Animals; Cell Membrane; Cells, Cultured; Colon; Cyclic AMP; Esophagus; Gastric Fundus; Gastrointesti | 2004 |
Characterisation of 5-HT2 receptor subtypes in the Suncus murinus intestine.
Topics: Amphetamines; Animals; Female; In Vitro Techniques; Indoles; Intestines; Male; Muscle Contraction; P | 1999 |