sb 203580 and Pregnancy

Topics: Amnion; Animals; Anthracenes; Cyclooxygenase 2; Dual-Specificity Phosphatases; Epithelial Cells; Female; Imidazoles; Inflammation; Labor, Obstetric; Male; MAP Kinase Signaling System; Mice; MicroRNAs; Pregnancy; Pyridines

Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Female; Humans; Imidazoles; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Pancreatitis, Acute Necrotizing; Pregnancy; Pregnancy Complications; Pyridines; Rats

Topics: Amnion; Cells, Cultured; Cellular Senescence; Epithelial Cells; Extraembryonic Membranes; Female; Humans; Imidazoles; Infections; Inflammation; Interleukin-6; Lipopolysaccharides; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pregnancy; Premature Birth; Primary Cell Culture; Pyridines; Tumor Necrosis Factor-alpha

Topics: Adult; Cellular Senescence; Chorioallantoic Membrane; Extraembryonic Membranes; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pregnancy; Progesterone; Pyridines; Rosuvastatin Calcium; Simvastatin; Smoke; Young Adult

Topics: Acute Disease; Acute Lung Injury; Animals; Female; Imidazoles; Inflammation; Interleukin-1beta; Lung; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pancreatitis; Phosphorylation; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha

Topics: Cell Line, Tumor; Choriocarcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Uterine Neoplasms

Topics: Animals; Butadienes; Cell Movement; Cell Proliferation; Chromones; Ectoderm; Female; Gene Expression Regulation; Imidazoles; Insulin-Like Growth Factor I; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Primary Cell Culture; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, IGF Type 1; Ribosomal Protein S6; RNA, Messenger; Signal Transduction; Swine; Trophoblasts

Topics: Antigens, CD; Diabetes, Gestational; Endoglin; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Imidazoles; Interleukin-6; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Placenta Growth Factor; Plasminogen Activator Inhibitor 1; Polymerase Chain Reaction; PPAR gamma; Pregnancy; Pregnancy Proteins; Pyridines; Receptors, Cell Surface; Rosiglitazone; Signal Transduction; Thiazolidinediones; Trophoblasts; Urokinase-Type Plasminogen Activator; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

Topics: Animals; Cells, Cultured; Chromatography, Liquid; DNA; Female; Flavonoids; Hepatocytes; Humans; Imidazoles; Male; MAP Kinase Signaling System; Mass Spectrometry; Placenta; Pregnancy; Protein Kinase Inhibitors; Pyridines; Pyrrolidonecarboxylic Acid; Rats, Sprague-Dawley

Topics: Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Down-Regulation; Female; Glucose; Guanylate Cyclase; Humans; Hyperglycemia; Imidazoles; Pregnancy; Pregnancy Trimester, First; Pyridines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Soluble Guanylyl Cyclase; Thiazolidinediones; Trophoblasts

Topics: Animals; Apoptosis; Blastocyst; Blastocyst Inner Cell Mass; Cell Death; Cell Lineage; Embryonic Development; Female; Gene Expression Regulation, Developmental; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Imidazoles; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Models, Biological; Pregnancy; Protein Kinase Inhibitors; Pyridines; RNA, Messenger

Topics: Acute Lung Injury; Animals; Disease Models, Animal; Estrogens; Female; Imidazoles; Interleukin-6; Lung; p38 Mitogen-Activated Protein Kinases; Peroxidase; Pregnancy; Protective Agents; Pyridines; Rabbits; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha

Topics: Blotting, Western; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Endoglin; Enzyme Inhibitors; Female; Humans; Imidazoles; Nuclear Proteins; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Placenta; Pre-Eclampsia; Pregnancy; Pyridines; Trophoblasts; Vascular Endothelial Growth Factor Receptor-1

Topics: Adenosine Triphosphate; Adult; Cell Differentiation; Cells, Cultured; Epidermal Growth Factor; Fatty Acids, Nonesterified; Female; Glycolysis; Humans; Imidazoles; Metabolic Flux Analysis; Microscopy, Fluorescence; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; p38 Mitogen-Activated Protein Kinases; Placenta; Pregnancy; Pyridines; Term Birth; Trophoblasts

Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Organogenesis; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Teratogens

Topics: Adiponectin; Animals; Butadienes; Embryonic Development; Female; Flavonoids; Imidazoles; Immunohistochemistry; Male; MAP Kinase Signaling System; Meiosis; Mitogen-Activated Protein Kinases; Nitriles; Oocytes; Parthenogenesis; Pregnancy; Protein Kinase Inhibitors; Pyridines; Receptors, Adiponectin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Swine

Topics: Benzoquinones; Cell Differentiation; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Activation; Female; Flavonoids; Focal Adhesion Protein-Tyrosine Kinases; Humans; Imidazoles; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Pregnancy; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Pyridines; Pyrimidines; Rifabutin; Signal Transduction; src-Family Kinases; Trophoblasts

Topics: Anthracenes; Butadienes; Cell Line; Cell Movement; Chemokine CCL2; Chemokine CCL5; Collagen; Culture Media, Conditioned; Drug Combinations; Enzyme Inhibitors; Female; Humans; Imidazoles; In Vitro Techniques; Laminin; Macrophages; MAP Kinase Signaling System; Monocytes; Nitriles; Pregnancy; Proteoglycans; Pyridines; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Trophoblasts; Tumor Necrosis Factor-alpha

Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Cardiomyopathies; Dose-Response Relationship, Drug; Electrocardiography; Enzyme Inhibitors; Female; Hemodynamics; Imidazoles; Immunoprecipitation; Isoproterenol; Male; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Tropomyosin

Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Cells, Cultured; Corticotropin-Releasing Hormone; Epidermal Growth Factor; Female; Gene Expression Regulation, Developmental; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Pyrimidines; RNA, Messenger; RNA, Small Interfering; Trophoblasts

Topics: Analysis of Variance; Animals; Benzimidazoles; Calcium; Carbocyanines; Cell Survival; Cells, Cultured; Cerebral Cortex; Clorgyline; Consensus Sequence; Embryo, Mammalian; Enzyme Inhibitors; Female; Humans; Imidazoles; Mice; Mitogen-Activated Protein Kinase 11; Monoamine Oxidase; Neurons; Phosphorylation; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serine; Signal Transduction; Transfection

Topics: Animals; Cell Adhesion; Chromatography, Affinity; Embryo Implantation; Enzyme Inhibitors; Female; Imidazoles; Immunoprecipitation; Integrin alpha5beta1; Integrin alphaVbeta3; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Signaling System; Microscopy, Fluorescence; Osteopontin; Phosphatidylinositol 3-Kinases; Phosphorylation; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; Ribosomal Protein S6 Kinases, 70-kDa; Sheep; Signal Transduction; TOR Serine-Threonine Kinases; Uterus

Topics: Androstadienes; Animals; Anthracenes; Arteries; Butadienes; Caveolin 1; Cell Movement; Cells, Cultured; CSK Tyrosine-Protein Kinase; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Enzyme Inhibitors; Female; Focal Adhesion Protein-Tyrosine Kinases; Imidazoles; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide Synthase Type III; Nitriles; Nitrogen Oxides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Placenta; Pregnancy; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Sheep; Signal Transduction; src-Family Kinases; Vascular Endothelial Growth Factor A; Wortmannin

Topics: Adult; Decidua; Estradiol; Female; Humans; Imidazoles; Immunohistochemistry; Interleukin-11; Interleukin-1beta; Naphthalenes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pre-Eclampsia; Pregnancy; Protein Kinase C; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Tumor Necrosis Factor-alpha

Topics: Adenosine Monophosphate; Cell Differentiation; Cell Line; Cell Proliferation; Chorionic Gonadotropin; Dimethyl Sulfoxide; Drug Evaluation; Female; Flavonoids; Fluorescent Antibody Technique; Fruit; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Placentation; Plant Extracts; Pregnancy; Pyridines; Rubiaceae; Signal Transduction; Trophoblasts

Topics: Blotting, Western; Cell Line; Cell Movement; Female; Gene Expression Regulation; HLA-G Antigens; Humans; Imidazoles; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pre-Eclampsia; Pregnancy; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Transfection; Trophoblasts

Topics: Animals; Cell Survival; Chromones; Enzyme Activation; Female; Free Radical Scavengers; Imidazoles; Male; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Sertoli Cells; Up-Regulation; Vitamin A

Topics: Butadienes; Cell Line, Tumor; Cell Survival; Enzyme-Linked Immunosorbent Assay; Female; Flavonoids; Humans; Imidazoles; Immunoblotting; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-E2-Related Factor 2; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pre-Eclampsia; Pregnancy; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A

Topics: Activating Transcription Factor 2; Animals; Animals, Newborn; Blotting, Western; Cell Division; Collagen Type I; Cyclic AMP Response Element-Binding Protein; Drug Synergism; Female; Fibroblasts; Fibronectins; Fibrosis; Flavonoids; Humans; Imidazoles; Luciferases; Myocardium; Nifedipine; Norepinephrine; Phosphorylation; Plasminogen Activator Inhibitor 1; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured

Topics: Animals; Butadienes; Cells, Cultured; Curcumin; Enzyme Inhibitors; Female; Flavonoids; Gene Expression; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth; Myometrium; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Uterine Contraction

Topics: Animals; Apoptosis; Blotting, Western; Cell Survival; Ceramides; Cerebral Cortex; Culture Media, Serum-Free; Culture Techniques; DNA-Binding Proteins; Early Growth Response Protein 1; Embryo, Mammalian; Enzyme Inhibitors; Female; Gene Expression Regulation; Green Fluorescent Proteins; Imidazoles; Immediate-Early Proteins; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Luminescent Proteins; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Proteins; Proto-Oncogene Proteins c-jun; Pyridines; Sphingosine; Subcellular Fractions; Time Factors; Transcription Factors; Transfection

Topics: Cell Division; Choriocarcinoma; Female; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Tetradecanoylphorbol Acetate; Uterine Neoplasms

Topics: Animals; Antioxidants; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Female; gamma-Tocopherol; HSP70 Heat-Shock Proteins; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Microglia; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesame Oil

Topics: Animals; Embryo, Mammalian; Embryonic and Fetal Development; Embryonic Development; Enzyme Inhibitors; Female; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Oocytes; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Zygote

Topics: Animals; Base Sequence; Cloning, Molecular; DNA Primers; Embryonic Development; Enzyme Inhibitors; Female; Fluorescent Antibody Technique, Indirect; Imidazoles; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

Topics: Activating Transcription Factor 2; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Carrier Proteins; Cell Death; Cell Survival; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Densitometry; Drug Interactions; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Glutamic Acid; Humans; Hyaluronan Receptors; Imidazoles; In Situ Nick-End Labeling; Male; Mitochondrial Proteins; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Pregnancy; Protein Subunits; Pyridines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors

Topics: Animals; Blotting, Western; Cadmium; Dinoprostone; Enzyme Inhibitors; Female; Flavonoids; Imidazoles; Kinetics; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; Phospholipases A; Phospholipases A2; Phosphorylation; Pregnancy; Protein Kinase C; Pyridines; Signal Transduction

Topics: Actins; alpha Catenin; Animals; Blastocyst; Cadherins; Cell Adhesion Molecules; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Embryonic Development; Enzyme Inhibitors; Female; Flavonoids; Fluorescent Antibody Technique, Indirect; Heat-Shock Proteins; Imidazoles; Intracellular Signaling Peptides and Proteins; Mice; Mitogen-Activated Protein Kinase 3; Morula; p38 Mitogen-Activated Protein Kinases; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; Pyrimidines; Signal Transduction; Time Factors

Topics: Adult; Blotting, Western; Cell Differentiation; Cell Separation; Chorionic Gonadotropin; Culture Media, Serum-Free; Densitometry; Enzyme Inhibitors; Female; Flavonoids; Fluorescent Antibody Technique; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Imidazoles; L-Lactate Dehydrogenase; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Placenta; Placental Lactogen; Pregnancy; Pyridines; Signal Transduction; Trophoblasts

Topics: Adaptor Proteins, Signal Transducing; Adult; Anthracenes; Apoptosis; Cell Culture Techniques; Chorionic Villi; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Female; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Pyridines; Signal Transduction; Trophoblasts

Topics: Cell Differentiation; Cell Fusion; Cell Proliferation; Cells, Cultured; Chorionic Gonadotropin, beta Subunit, Human; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Female; Humans; Imidazoles; Mitogen-Activated Protein Kinase 11; Mitogen-Activated Protein Kinase 14; Organ Culture Techniques; Placenta; Pregnancy; Pyridines; Trophoblasts

Topics: Animals; Apoptosis; Caspases; Corpus Luteum; Female; Gonadotropin-Releasing Hormone; Imidazoles; Intracellular Signaling Peptides and Proteins; Macaca radiata; MAP Kinase Kinase 3; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Pregnancy; Protein Serine-Threonine Kinases; Pyridines

Topics: Blotting, Western; Butadienes; Cells, Cultured; Coumarins; Cyclic AMP; Cyclooxygenase 2; Female; Gene Expression; Humans; I-kappa B Kinase; Imidazoles; Interleukin-1beta; Labor Onset; Membrane Proteins; Microscopy, Confocal; Mitogen-Activated Protein Kinase 3; Myocytes, Smooth Muscle; Myometrium; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Receptors, Corticotropin-Releasing Hormone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

Topics: Cells, Cultured; Corticotropin-Releasing Hormone; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Pregnancy; Pyridines; Toll-Like Receptor 4; Trophoblasts; Tumor Necrosis Factor-alpha

Topics: Blotting, Western; Chorioamnionitis; Decidua; Enzyme-Linked Immunosorbent Assay; Female; Humans; Imidazoles; Immunohistochemistry; Interleukin-1beta; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Medroxyprogesterone Acetate; Obstetric Labor, Premature; Pregnancy; Progesterone Congeners; Protein Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

Topics: Calcium; Carcinogens; Cells, Cultured; Chorion; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Humans; Hydroxyprostaglandin Dehydrogenases; Imidazoles; Indoles; Maleimides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase 4; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Pregnancy; Protein Kinase C; Pyridines; RNA, Messenger; Tetradecanoylphorbol Acetate; Trophoblasts

Topics: Animals; Animals, Newborn; Apoptosis; Basal Ganglia; Cerebral Cortex; Corpus Striatum; Cytokines; Enzyme Inhibitors; Female; Gene Expression; Imidazoles; Immunohistochemistry; Injections, Subcutaneous; Interleukin-1beta; Interleukin-6; Neuroglia; Neurons; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Glutamate; Tumor Necrosis Factor-alpha

Topics: Animals; Cyclooxygenase 2; Decidua; Enzyme Activation; Enzyme Inhibitors; Female; Imidazoles; Isoenzymes; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Oils; p38 Mitogen-Activated Protein Kinases; Phenotype; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Uterus