sb 203580 has been researched along with Liver Neoplasms in 24 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (4.17) | 18.2507 |
2000's | 8 (33.33) | 29.6817 |
2010's | 11 (45.83) | 24.3611 |
2020's | 4 (16.67) | 2.80 |
Authors | Studies |
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He, H; Jia, Y; Peng, L; Qiao, K; Wang, C; Xu, Z; Yang, W; Zhang, C; Zhang, Z | 1 |
Dong, J; Hu, A; Jiang, L; Liang, Y; Sun, C; Tian, B; Wang, H; Wang, S | 1 |
Chen, J; Chen, X; Chu, L; Ding, Z; Guo, T; Hou, R; Huang, Z; Liang, H; Liang, J; Liao, J; Liu, S; Song, S; Tan, X; Wang, Y; Wen, J; Wu, Y; Yang, C; Zhang, B; Zhang, J; Zhang, Z | 1 |
Bai, X; Bao, Y; Li, H; Li, X; Liu, L; Suvesh, M; Xu, D | 1 |
Gui, S; Huang, D; Liu, H; Shao, D; Wang, Y; Wei, W; Zhang, L; Zhou, Q | 1 |
Rui, X; Yan, X; Zhang, K | 1 |
Liu, X; Lv, Y; Shi, J; Xiang, J; Zhang, X | 1 |
Jian, KL; Kong, LY; Shang, ZC; Yang, L; Zhang, C | 1 |
Kim, JR; Lee, KH | 1 |
Huang, SM; Kim, J; Kim, JM; Kim, NS; Kim, SU; Lee, DS; Oh, NS; Song, IS; Yu, DY | 1 |
Lee, WY; Liu, KW; Yeung, JH | 1 |
Sun, S; Tang, Y; Wang, F; Wang, Y; Yang, F; Yin, Y; Zhang, L | 1 |
Bai, ST; Chen, WC; Chung, JG; Huang, CH; Huang, LJ; Hung, CM; Kuo, SC; Tsai, JY; Way, TD | 1 |
Qian, ZY; Qiu, JW; Shen, LJ; Yu, J; Zhang, HX | 1 |
Liu, H; Ruan, J; Wei, A; Xiao, Y; Xiong, C | 1 |
Anwar-Mohamed, A; Denison, MS; El-Kadi, AO; Korashy, HM; Soshilov, AA | 1 |
Chen, GG; Chun, S; Lai, PB; Leung, BC; Zhang, H; Zhang, Z | 1 |
Chen, X; Duan, L; He, T; Luo, J; Shi, Q; Tang, M; Wang, H; Weng, Y; Wu, R; Yang, X; Ye, L; Zhang, Y; Zhou, L | 1 |
Roberts, RA | 1 |
Bronk, SF; Gores, GJ; Guicciardi, ME; Werneburg, NW | 1 |
Kaneoka, Y; Kozawa, O; Kumada, T; Matsushima-Nishiwaki, R; Takai, S; Tokuda, H; Toyoda, H; Yamaguchi, A; Yasuda, E | 1 |
Lou, L; Quan, H; Xu, Y | 1 |
Ben-Levy, R; Krupsky, M; Zauberman, A; Zipori, D | 1 |
Dokter, WH; Jonk, LJ; Kruijer, W; Schuringa, JJ; Vellenga, E | 1 |
1 review(s) available for sb 203580 and Liver Neoplasms
Article | Year |
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Evidence for cross talk between PPARalpha and p38 MAP kinase.
Topics: Animals; Carcinogens; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Hepatocytes; Imidazoles; Liver Neoplasms; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferators; Pyridines; Rats; Receptor Cross-Talk; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Transcription Factors | 2002 |
23 other study(ies) available for sb 203580 and Liver Neoplasms
Article | Year |
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Hydrazinocurcumin Induces Apoptosis of Hepatocellular Carcinoma Cells Through the p38 MAPK Pathway.
Topics: Animals; Carcinoma, Hepatocellular; Cell Proliferation; Curcumin; Hep G2 Cells; Humans; Hydrazines; Imidazoles; Liver Neoplasms; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Toxicity Tests, Subacute; Xenograft Model Antitumor Assays | 2021 |
ADAM17-regulated CX3CL1 expression produced by bone marrow endothelial cells promotes spinal metastasis from hepatocellular carcinoma.
Topics: ADAM17 Protein; Adult; Aged; Animals; Bone Marrow; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CX3CL1; Endothelial Progenitor Cells; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Imidazoles; Liver Neoplasms; Male; Mice; Middle Aged; Mitogen-Activated Protein Kinase 14; Pyridines; Receptors, CXCR3; RNA, Small Interfering; Signal Transduction; Spinal Neoplasms; Spine; Tumor Microenvironment | 2020 |
H19 Promotes HCC Bone Metastasis Through Reducing Osteoprotegerin Expression in a Protein Phosphatase 1 Catalytic Subunit Alpha/p38 Mitogen-Activated Protein Kinase-Dependent Manner and Sponging microRNA 200b-3p.
Topics: Animals; Bone Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Imidazoles; Liver Neoplasms; Male; Mice; MicroRNAs; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Protein Phosphatase 1; Pyridines; RAW 264.7 Cells; RNA, Long Noncoding; Up-Regulation; Zinc Finger E-box-Binding Homeobox 1 | 2021 |
Ebp1 p48 promotes oncogenic properties in hepatocellular carcinoma through p38 MAPK/HIF1α activation and p53 downregulation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Liver Neoplasms; Male; MAP Kinase Signaling System; Mice; Neoplasm Transplantation; p38 Mitogen-Activated Protein Kinases; Protein Isoforms; Pyridines; RNA-Binding Proteins; Survival Analysis; Tissue Array Analysis; Tumor Suppressor Protein p53 | 2021 |
Fenretinide inhibits the proliferation and migration of human liver cancer HepG2 cells by downregulating the activation of myosin light chain kinase through the p38‑MAPK signaling pathway.
Topics: Apoptosis; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Fenretinide; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Imidazoles; Liver Neoplasms; Myosin-Light-Chain Kinase; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Signal Transduction | 2018 |
Curcumin inhibits the proliferation and invasiveness of MHCC97-H cells via p38 signaling pathway.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Curcumin; Drug Synergism; Humans; Imidazoles; Liver Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Phosphorylation; Pyridines | 2014 |
Overexpression of syntenin enhances hepatoma cell proliferation and invasion: potential roles in human hepatoma.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Liver Neoplasms; Matrix Metalloproteinase 2; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Small Interfering; Signal Transduction; Syntenins | 2014 |
Eucalrobusone C suppresses cell proliferation and induces ROS-dependent mitochondrial apoptosis via the p38 MAPK pathway in hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Enzyme Inhibitors; Eucalyptus; Hep G2 Cells; Humans; Imidazoles; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; p38 Mitogen-Activated Protein Kinases; Phytotherapy; Plant Extracts; Pyridines; Reactive Oxygen Species | 2017 |
Reactive oxygen species regulate the generation of urokinase plasminogen activator in human hepatoma cells via MAPK pathways after treatment with hepatocyte growth factor.
Topics: Cell Line, Tumor; Fluorescent Dyes; Hepatocyte Growth Factor; Humans; Hydrogen Peroxide; Imidazoles; Liver Neoplasms; Mitogen-Activated Protein Kinases; Pyridines; rac1 GTP-Binding Protein; Reactive Oxygen Species; Recombinant Proteins; Urokinase-Type Plasminogen Activator | 2009 |
Peroxiredoxin I contributes to TRAIL resistance through suppression of redox-sensitive caspase activation in human hepatoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Imidazoles; Liver Neoplasms; NADPH Oxidase 4; NADPH Oxidases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Peroxiredoxins; Pyridines; Reactive Oxygen Species; TNF-Related Apoptosis-Inducing Ligand | 2009 |
Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells.
Topics: Abietanes; Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Activation; Furans; Humans; Imidazoles; Inhibitory Concentration 50; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Liver Neoplasms; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Protein Transport; Pyridines; Quinones; Reactive Oxygen Species; Time Factors | 2009 |
miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; E2F1 Transcription Factor; HSP27 Heat-Shock Proteins; Humans; Imidazoles; Liver Neoplasms; MicroRNAs; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Protein Phosphatase 2C; Pyridines; RNA, Small Interfering | 2010 |
Induction of apoptosis by HAC-Y6, a novel microtubule inhibitor, through activation of the death receptor 4 signaling pathway in human hepatocellular carcinoma cells.
Topics: Animals; Apoptosis; Carbolines; Carcinoma, Hepatocellular; Caspases; Cell Growth Processes; Cell Line, Tumor; Humans; Imidazoles; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubules; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; Up-Regulation; Xenograft Model Antitumor Assays | 2010 |
[Role of p38MAPK in apoptosis of human paratumor cirrhosis hepatocellular cell line QSG-7701 induced by cisplatin].
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cisplatin; Humans; Imidazoles; Liver Neoplasms; p38 Mitogen-Activated Protein Kinases; Pyridines | 2010 |
Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.
Topics: Acetylcysteine; Anthracenes; Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Survival; Cyclohexanones; Enzyme Activation; Flavones; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Imidazoles; Intracellular Space; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reactive Oxygen Species | 2011 |
The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation.
Topics: Animals; Carcinoma, Hepatocellular; Cell Survival; Cytochrome P-450 CYP1A1; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Guinea Pigs; Hep G2 Cells; Humans; Imidazoles; Liver Neoplasms; Male; Mice; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Aryl Hydrocarbon; Transcriptional Activation | 2011 |
Induction of autophagy in hepatocellular carcinoma cells by SB203580 requires activation of AMPK and DAPK but not p38 MAPK.
Topics: AMP-Activated Protein Kinases; Apoptosis Regulatory Proteins; Autophagy; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Hepatocellular; Cell Line, Tumor; Death-Associated Protein Kinases; Enzyme Inhibitors; Humans; Imidazoles; Liver Neoplasms; p38 Mitogen-Activated Protein Kinases; Pyridines | 2012 |
S100A9 promotes the proliferation and invasion of HepG2 hepatocellular carcinoma cells via the activation of the MAPK signaling pathway.
Topics: Animals; Calgranulin B; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Hep G2 Cells; Humans; Imidazoles; Liver Neoplasms; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Transplantation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Random Allocation; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2013 |
cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis.
Topics: Apoptosis; Butadienes; Carcinoma, Hepatocellular; CASP8 and FADD-Like Apoptosis Regulating Protein; Cathepsins; Cell Line, Tumor; Flavonoids; Humans; Imidazoles; Liver Neoplasms; Lysosomes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; p38 Mitogen-Activated Protein Kinases; Permeability; Protein Transport; Pyridines; TNF-Related Apoptosis-Inducing Ligand | 2007 |
Protein kinase C delta regulates the phosphorylation of heat shock protein 27 in human hepatocellular carcinoma.
Topics: Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Heat-Shock Proteins; Humans; Imidazoles; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-delta; Pyridines; RNA, Small Interfering; Tetradecanoylphorbol Acetate | 2007 |
p38 MAPK, but not ERK1/2, is critically involved in the cytotoxicity of the novel vascular disrupting agent combretastatin A4.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fluorescent Antibody Technique; Humans; Imidazoles; Liver Neoplasms; Male; Microtubules; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Pyridines; Stilbenes; Time Factors | 2008 |
Stress activated protein kinase p38 is involved in IL-6 induced transcriptional activation of STAT3.
Topics: Acute-Phase Proteins; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Hepatocellular; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Genes, Reporter; Haptoglobins; HL-60 Cells; Humans; Imidazoles; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Mice; Mitogen-Activated Protein Kinases; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Pyridines; Recombinant Fusion Proteins; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Transcriptional Activation; Tumor Cells, Cultured | 1999 |
Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components.
Topics: Amino Acid Substitution; Carcinoma, Hepatocellular; Cell Cycle Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Genes, Reporter; Humans; Imidazoles; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Pyridines; rac GTP-Binding Proteins; Recombinant Proteins; Serine; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2000 |