Page last updated: 2024-09-05

sb 203580 and Invasiveness, Neoplasm

sb 203580 has been researched along with Invasiveness, Neoplasm in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.00)18.2507
2000's17 (42.50)29.6817
2010's21 (52.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cho, SB; Joo, YE; Lee, WS; Myung, DS; Oh, HH; Park, D; Park, SY; Park, YL; Yu, HM1
Guan, Q; Ma, Q; Nan, Y; Wang, H; Zhong, Y1
Chang, SL; Fong, YC; Hsu, CJ; Lin, CY; Tang, CH1
Chen, GG; Liu, X; Ng, EK; To, KF; Wang, C; Wu, WK; Yu, J1
Rui, X; Yan, X; Zhang, K1
Chay, KO; Joo, YE; Jung, YD; Khoi, PN; Kim, KK; Lian, S; Xia, Y; Yoon, HJ1
Liu, X; Lv, Y; Shi, J; Xiang, J; Zhang, X1
Cai, F; Guo, L; Liu, X; Xu, P1
Beccafico, S; Donato, R; Marchetti, MC; Morozzi, G; Riccardi, C; Sidoni, A; Sorci, G1
Aroui, S; Chtourou, Y; Fetoui, H; Kenani, A; Laajimi, A; Meunier, AC; Najlaoui, F1
Cao, Q; Chen, GL; Fang, WH; Jiang, XR; Li, HH; Li, M; Li, Y; Liu, X; Ping, GF; Wang, LH; Wang, S; Wu, CF; Yang, JY1
Li, ZX; Qiu, XS; Sun, LM; Xia, ZX; Zhang, M; Zhang, QF1
Gao, FH; Liu, H; Tang, MC; Xu, XF; Zhao, Y; Zhou, YQ1
Hwang, HS; Jittreetat, T; Kim, CH; Kim, YS; Lee, BS; Sannikorn, P; Shin, YS1
Cao, L; Chen, X; Li, W; Ma, Q; Xiao, X1
Ji, Q; Ling, G; Ma, D; Wang, Y; Ye, W1
Kim, JR; Lee, KH2
Hwa, JS; Khandrika, L; Koul, HK; Koul, S; Kumar, B; Meacham, RB; Petersen, J; Wilson, S1
del Barco Barrantes, I; Nebreda, AR1
Gu, M; Liang, H; Wang, H; Wen, X; Yang, C; Zhou, Q1
Chen, X; Duan, L; He, T; Luo, J; Shi, Q; Tang, M; Wang, H; Weng, Y; Wu, R; Yang, X; Ye, L; Zhang, Y; Zhou, L1
Benbow, U; Brinckerhoff, CE; Buttice, G; Tower, GB; Wyatt, CA1
Berger, S; Denkert, C; Hauptmann, S; Köbel, M; Koch, I; Siegert, A1
Chen, SL; Chen, SM; Li, H; Luo, R; Pang, ZJ; Xing, FQ; Zhang, XQ; Zhao, XS1
Ben-Ze'ev, A; Kosakowski, M; Lee, P; Libertino, JA; Moinzadeh, A; Rieger-Christ, KM; Stoffel, J; Summerhayes, IC; Zagha, R1
Chen, L; Fang, WG; Heng, WJ; You, JF1
Chung, TW; Kim, CH; Lee, YC1
Behren, A; Binder, K; Herberhold, S; Hirt, B; Loewenheim, H; Preyer, S; Simon, C; Vucelic, G; Zenner, HP1
Chen, L; Fang, WG; He, HY; Heng, WJ; Li, HM; Li, Y; You, JF1
Bakin, AV; Cowell, JK; Li, X; Ranalli, TA; Sossey-Alaoui, K1
Bergan, RC; Chen, S; Xu, L1
Bae, YS; Kim, JM; Kim, MK; Kim, SD; Lee, HY; Lee, SY; Park, KS; Ryu, SH1
Chang, HC; Chang, SH; Hung, WC1
Boyd, D; Goepfert, H; Simon, C1
Montero, L; Nagamine, Y1
Han, J; Huang, S; Nemerow, GR; New, L; Pan, Z1
Hicks, MJ; Koitschev, A; Plinkert, PK; Simon, C; Simon, M; Vucelic, G; Zenner, HP1
Grijalva, R; Klos, K; Li, P; Nguyen, N; Xiong, S; Yao, J; Yu, D1
Denkert, C; Hauptmann, S; Leclere, A; Siegert, A; Turzynski, A1

Reviews

1 review(s) available for sb 203580 and Invasiveness, Neoplasm

ArticleYear
Roles of p38 MAPKs in invasion and metastasis.
    Biochemical Society transactions, 2012, Volume: 40, Issue:1

    Topics: Animals; Anoikis; Epithelial-Mesenchymal Transition; Humans; Imidazoles; MAP Kinase Signaling System; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neoplastic Cells, Circulating; p38 Mitogen-Activated Protein Kinases; Pyridines

2012

Other Studies

39 other study(ies) available for sb 203580 and Invasiveness, Neoplasm

ArticleYear
Malformin A1 treatment alters invasive and oncogenic phenotypes of human colorectal cancer cells through stimulation of the p38 signaling pathway.
    International journal of oncology, 2017, Volume: 51, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Humans; Imidazoles; MAP Kinase Signaling System; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Pyridines; Tumor Suppressor Protein p53; X-Linked Inhibitor of Apoptosis Protein

2017
Overexpression of human MX2 gene suppresses cell proliferation, migration, and invasion via ERK/P38/NF-κB pathway in glioblastoma cells.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:11

    Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Imidazoles; Myxovirus Resistance Proteins; Neoplasm Invasiveness; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Pyridines; Signal Transduction; Thiocarbamates

2019
Apoptosis signal-regulating kinase 1 is involved in brain-derived neurotrophic factor (BDNF)-enhanced cell motility and matrix metalloproteinase 1 expression in human chondrosarcoma cells.
    International journal of molecular sciences, 2013, Jul-25, Volume: 14, Issue:8

    Topics: Anthracenes; Bone Neoplasms; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Line, Tumor; Cell Movement; Chondrosarcoma; Humans; Imidazoles; Indole Alkaloids; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; Matrix Metalloproteinase 1; Neoplasm Invasiveness; Neoplasm Metastasis; p38 Mitogen-Activated Protein Kinases; Prognosis; Protein Kinases; Pyridines; Receptor, trkB; Signal Transduction; Thioredoxins; Up-Regulation

2013
Increased serum chemerin level promotes cellular invasiveness in gastric cancer: a clinical and experimental study.
    Peptides, 2014, Volume: 51

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Case-Control Studies; Cell Line, Tumor; Chemokines; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Male; MAP Kinase Signaling System; Middle Aged; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Receptors, Chemokine; Stomach Neoplasms

2014
Curcumin inhibits the proliferation and invasiveness of MHCC97-H cells via p38 signaling pathway.
    Drug development research, 2014, Volume: 75, Issue:7

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Curcumin; Drug Synergism; Humans; Imidazoles; Liver Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Phosphorylation; Pyridines

2014
Piperine inhibits IL-1β-induced IL-6 expression by suppressing p38 MAPK and STAT3 activation in gastric cancer cells.
    Molecular and cellular biochemistry, 2015, Volume: 398, Issue:1-2

    Topics: Alkaloids; Benzodioxoles; Blotting, Western; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Interleukin-1beta; Interleukin-6; Mutation; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Piperidines; Polyunsaturated Alkamides; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; STAT3 Transcription Factor; Stomach Neoplasms; UDPglucose 4-Epimerase

2015
Overexpression of syntenin enhances hepatoma cell proliferation and invasion: potential roles in human hepatoma.
    Oncology reports, 2014, Volume: 32, Issue:6

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Liver Neoplasms; Matrix Metalloproteinase 2; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Small Interfering; Signal Transduction; Syntenins

2014
Sesamin inhibits lipopolysaccharide-induced proliferation and invasion through the p38-MAPK and NF-κB signaling pathways in prostate cancer cells.
    Oncology reports, 2015, Volume: 33, Issue:6

    Topics: Cell Line, Tumor; Cell Proliferation; Cytokines; Dioxoles; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lignans; Lipopolysaccharides; Male; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostatic Neoplasms; Pyridines; Signal Transduction

2015
Artesunate induces ROS- and p38 MAPK-mediated apoptosis and counteracts tumor growth in vivo in embryonal rhabdomyosarcoma cells.
    Carcinogenesis, 2015, Volume: 36, Issue:9

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Artemisinins; Artesunate; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Damage; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Integrin beta1; Mice; MicroRNAs; Neoplasm Invasiveness; Neoplasm Transplantation; Neural Cell Adhesion Molecules; p38 Mitogen-Activated Protein Kinases; PAX7 Transcription Factor; Pyridines; Reactive Oxygen Species; Rhabdomyosarcoma, Embryonal; Transplantation, Heterologous

2015
Naringin inhibits the invasion and migration of human glioblastoma cell via downregulation of MMP-2 and MMP-9 expression and inactivation of p38 signaling pathway.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:3

    Topics: Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Flavanones; Glioblastoma; Humans; Imidazoles; Immunoblotting; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2

2016
SL4, a chalcone-based compound, induces apoptosis in human cancer cells by activation of the ROS/MAPK signalling pathway.
    Cell proliferation, 2015, Volume: 48, Issue:6

    Topics: Animals; Anthracenes; Apoptosis; bcl-X Protein; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Enzyme Activation; Female; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1; Imidazoles; Inhibitor of Apoptosis Proteins; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Pyridines; Reactive Oxygen Species; Survivin; X-Linked Inhibitor of Apoptosis Protein

2015
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.
    Experimental and molecular pathology, 2016, Volume: 100, Issue:2

    Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Non-Small-Cell Lung; CARD Signaling Adaptor Proteins; Caspase 3; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; MAP Kinase Signaling System; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription Factor RelA

2016
NS-398 promotes pancreatic cancer cell invasion by CD147 and MMP-2 via the activation of P38.
    Molecular medicine reports, 2016, Volume: 13, Issue:3

    Topics: Basigin; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Humans; Imidazoles; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Pyridines; RNA, Small Interfering; Sulfonamides

2016
Tolfenamic Acid Inhibits the Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma: Involvement of p38-Mediated Down-Regulation of Slug.
    Yonsei medical journal, 2016, Volume: 57, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Down-Regulation; Gastropoda; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Imidazoles; MAP Kinase Signaling System; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; ortho-Aminobenzoates; Phosphorylation; Pyridines

2016
Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: Acetylcysteine; Cell Line, Tumor; Cell Movement; Diabetes Complications; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glucose; Humans; Hyperglycemia; Imidazoles; MAP Kinase Signaling System; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Pyridines; Reactive Oxygen Species; Resveratrol; Stilbenes

2016
Epithelial-mesenchymal transition regulated by p38/MAPK signaling pathways participates in vasculogenic mimicry formation in SHG44 cells transfected with TGF-β cDNA loaded lentivirus in vitro and in vivo.
    International journal of oncology, 2016, Volume: 49, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Movement; Cell Plasticity; Cell Proliferation; Epithelial-Mesenchymal Transition; Glioma; Humans; Imidazoles; Lentivirus; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; p38 Mitogen-Activated Protein Kinases; Pyridines; Transfection; Transforming Growth Factor beta; Transplantation, Heterologous

2016
Kiss-1 suppresses MMP-9 expression by activating p38 MAP kinase in human stomach cancer.
    Oncology research, 2009, Volume: 18, Issue:2-3

    Topics: Cell Line, Tumor; Cell Proliferation; Down-Regulation; Enzyme Activation; Flavonoids; Gene Expression Regulation, Enzymologic; Hepatocyte Growth Factor; Humans; Imidazoles; Kisspeptins; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Pyridines; Stomach Neoplasms; Tumor Suppressor Proteins

2009
p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity.
    Cancer research, 2010, Jan-15, Volume: 70, Issue:2

    Topics: Cell Growth Processes; Cell Line, Tumor; Cell Movement; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; RNA, Messenger; Transfection; Urinary Bladder Neoplasms

2010
Regulation of HGF-mediated cell proliferation and invasion through NF-κB, JunB, and MMP-9 cascades in stomach cancer cells.
    Clinical & experimental metastasis, 2012, Volume: 29, Issue:3

    Topics: Cell Line, Tumor; Cell Proliferation; Hepatocyte Growth Factor; Humans; Imidazoles; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; Pyridines; Stomach Neoplasms; Transcription Factor AP-1

2012
Sevoflurane inhibits invasion and migration of lung cancer cells by inactivating the p38 MAPK signaling pathway.
    Journal of anesthesia, 2012, Volume: 26, Issue:3

    Topics: Anesthetics, Inhalation; Cell Line, Tumor; Cell Movement; Humans; Imidazoles; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase Inhibitors; Methyl Ethers; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sevoflurane

2012
S100A9 promotes the proliferation and invasion of HepG2 hepatocellular carcinoma cells via the activation of the MAPK signaling pathway.
    International journal of oncology, 2013, Volume: 42, Issue:3

    Topics: Animals; Calgranulin B; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Hep G2 Cells; Humans; Imidazoles; Liver Neoplasms; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Transplantation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Random Allocation; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays

2013
High levels of MMP-1 expression in the absence of the 2G single nucleotide polymorphism is mediated by p38 and ERK1/2 mitogen-activated protein kinases in VMM5 melanoma cells.
    Journal of cellular biochemistry, 2002, Volume: 86, Issue:2

    Topics: Collagen Type I; DNA; DNA-Binding Proteins; Flavonoids; Gene Expression Regulation, Enzymologic; Imidazoles; Matrix Metalloproteinase 1; Melanoma; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Pyridines; Signal Transduction; Transcription Factors; Transfection; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

2002
Cytokine-suppressive anti-inflammatory drugs (CSAIDs) inhibit invasion and MMP-1 production of ovarian carcinoma cells.
    Cancer letters, 2003, May-30, Volume: 195, Issue:1

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Cytokines; Drug Combinations; Enzyme Induction; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Inflammation; Interleukin-1; Laminin; MAP Kinase Kinase 1; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Proteins; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteoglycans; Pyridines; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2003
[Role of p38 pathway in PMA-induced in vitro invasion of JAR human choriocarcinoma cell line].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:8

    Topics: Cell Division; Choriocarcinoma; Female; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Tetradecanoylphorbol Acetate; Uterine Neoplasms

2003
Novel expression of N-cadherin elicits in vitro bladder cell invasion via the Akt signaling pathway.
    Oncogene, 2004, Jun-10, Volume: 23, Issue:27

    Topics: Blotting, Western; Cadherins; Carcinoma; Cell Line, Tumor; Chromones; Clone Cells; Collagen; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Immunohistochemistry; Laminin; Morpholines; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proteoglycans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Pyridines; Serine; Signal Transduction; Transfection; Urinary Bladder Neoplasms

2004
[Effects of P2Y receptor activation on prostatic cancer cells requiring ERK1/2 or p38 cascade].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2004, Volume: 33, Issue:2

    Topics: Adenosine Triphosphate; Cell Line, Tumor; Cell Proliferation; Humans; Imidazoles; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Pyridines; Receptors, Purinergic P2; Transfection

2004
Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:10

    Topics: Androstadienes; Butadienes; Cell Line; Enzyme Inhibitors; Gene Expression Regulation, Viral; Hepatitis B virus; Hepatocytes; Humans; Imidazoles; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Recombinant Fusion Proteins; Signal Transduction; Trans-Activators; Transcription, Genetic; Transfection; Viral Regulatory and Accessory Proteins; Wortmannin

2004
The p38 SAPK pathway is required for Ha-ras induced in vitro invasion of NIH3T3 cells.
    Experimental cell research, 2005, Feb-15, Volume: 303, Issue:2

    Topics: Animals; Base Sequence; DNA; Gene Expression Regulation; Genes, ras; Imidazoles; In Vitro Techniques; Isoenzymes; MAP Kinase Signaling System; Mice; Neoplasm Invasiveness; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Pyridines; Transfection; Urokinase-Type Plasminogen Activator

2005
[ERK1/2 and p38 kinases are important regulators in P2Y receptor-mediated prostate cancer invasion].
    Zhonghua yi xue za zhi, 2005, Jan-12, Volume: 85, Issue:2

    Topics: Cell Line, Tumor; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Pyridines; Receptors, Purinergic P2; Signal Transduction

2005
WAVE3 promotes cell motility and invasion through the regulation of MMP-1, MMP-3, and MMP-9 expression.
    Experimental cell research, 2005, Aug-01, Volume: 308, Issue:1

    Topics: Actins; Adenocarcinoma; Cell Line, Tumor; Cell Movement; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Imidazoles; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Microfilament Proteins; Neoplasm Invasiveness; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Time Factors; Wiskott-Aldrich Syndrome Protein Family

2005
MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer.
    Oncogene, 2006, May-18, Volume: 25, Issue:21

    Topics: Adenocarcinoma; Cell Line, Tumor; Enzyme Activation; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Male; Matrix Metalloproteinase 2; Molecular Chaperones; Neoplasm Invasiveness; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Transfection; Transforming Growth Factor beta

2006
S1P stimulates chemotactic migration and invasion in OVCAR3 ovarian cancer cells.
    Biochemical and biophysical research communications, 2007, Apr-27, Volume: 356, Issue:1

    Topics: Blotting, Western; Calcium; Cell Line, Tumor; Cell Movement; Chemotaxis; Chromones; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lysophospholipids; Morpholines; Neoplasm Invasiveness; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Protein Isoforms; Proto-Oncogene Proteins c-akt; Pyridines; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sphingosine

2007
Transcriptional repression of tissue inhibitor of metalloproteinase-3 by Epstein-Barr virus latent membrane protein 1 enhances invasiveness of nasopharyngeal carcinoma cells.
    Oral oncology, 2008, Volume: 44, Issue:9

    Topics: Carcinoma, Squamous Cell; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Pyridines; Tissue Inhibitor of Metalloproteinase-3; Transcription Factors; Tumor Cells, Cultured; Viral Matrix Proteins

2008
Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion.
    Cancer research, 1998, Mar-15, Volume: 58, Issue:6

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Collagenases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Head and Neck Neoplasms; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Regulation by p38 mitogen-activated protein kinase of adenylate- and uridylate-rich element-mediated urokinase-type plasminogen activator (uPA) messenger RNA stability and uPA-dependent in vitro cell invasion.
    Cancer research, 1999, Oct-15, Volume: 59, Issue:20

    Topics: 3' Untranslated Regions; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1999
Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38alpha mitogen-activated protein kinase activity.
    The Journal of biological chemistry, 2000, Apr-21, Volume: 275, Issue:16

    Topics: Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Inhibitors; Extracellular Matrix; Female; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

2000
The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation.
    Experimental cell research, 2001, Dec-10, Volume: 271, Issue:2

    Topics: Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Imidazoles; MAP Kinase Kinase 6; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Mutation; Neoplasm Invasiveness; Neoplasms; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Isoforms; Protein Structure, Tertiary; Proto-Oncogene Proteins c-jun; Pyridines; Signal Transduction; Terminal Repeat Sequences; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured

2001
Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells.
    Oncogene, 2001, Dec-06, Volume: 20, Issue:56

    Topics: Breast Neoplasms; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Indoles; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Neoplasm Invasiveness; Neuregulin-1; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; RNA, Neoplasm; Signal Transduction; Transcriptional Activation; Tumor Cells, Cultured

2001
An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells.
    Clinical & experimental metastasis, 2002, Volume: 19, Issue:1

    Topics: Blotting, Northern; Cell Division; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Gelatin; Gene Expression Regulation, Neoplastic; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Melanoma; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pyridines; RNA, Messenger; RNA, Neoplasm; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured

2002