Page last updated: 2024-09-05

sb 203580 and Chronic Illness

sb 203580 has been researched along with Chronic Illness in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Albrecht, W; Kotschenreuther, DA; Laufer, SA; Wagner, GK1
Albrecht, W; Bauer, SM; Laufer, SA; Unger, A1
Choi, H; Dikalov, SI; Koch, SR; Lamb, FS; Mace, EH; Sherwood, ER; Stark, RJ1
Chen, J; Dong, J; Fu, C; Guo, Z; Li, N; Liu, Y; Wang, R; Wang, S; Yang, J; Yuan, Y; Zhang, Y1
Feng, XR; Liu, ZC; Lu, HD; Wang, B; Zhou, J; Zhou, LY1
Huang, Y; Xu, L; Yang, N; Yu, X; Yue, J; Zuo, P1

Other Studies

6 other study(ies) available for sb 203580 and Chronic Illness

ArticleYear
Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes.
    Journal of medicinal chemistry, 2003, Jul-17, Volume: 46, Issue:15

    Topics: Aminopyridines; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cytochrome P-450 Enzyme System; Cytokines; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-1; Isoenzymes; Leukocytes, Mononuclear; Liver; Mitogen-Activated Protein Kinases; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Pyridines; Stereoisomerism; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2003
Discovery of N-{4-[5-(4-Fluorophenyl)-3-methyl-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-acetamide (CBS-3595), a Dual p38α MAPK/PDE-4 Inhibitor with Activity against TNFα-Related Diseases.
    Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13

    Topics: Aminopyridines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Discovery; Humans; Imidazoles; Inflammation; Mitogen-Activated Protein Kinase 14; Phosphodiesterase 4 Inhibitors; Protein Kinase Inhibitors; Tumor Necrosis Factor-alpha

2017
Endothelial nitric oxide synthase modulates Toll-like receptor 4-mediated IL-6 production and permeability via nitric oxide-independent signaling.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Volume: 32, Issue:2

    Topics: Capillary Permeability; Cells, Cultured; Chronic Disease; Endothelial Cells; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Interleukin-6; Lipopolysaccharides; MAP Kinase Signaling System; Nitric Oxide; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Pyridines; Toll-Like Receptor 4; Vasculitis

2018
Chronic intermittent hypobaric hypoxia provides vascular protection in the aorta of the 2-kidney, 1-clip rat model of hypertension.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:8

    Topics: Acetylcholine; Animals; Anthracenes; Aorta; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Body Weight; Bone Morphogenetic Protein 4; Carrier Proteins; Chronic Disease; Disease Models, Animal; Endothelium, Vascular; Flavonoids; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; In Vitro Techniques; Kidney; Male; Nitric Oxide Synthase Type III; Nitroprusside; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats, Sprague-Dawley; Surgical Instruments; Systole; Vasodilation

2018
Influence of the TLR4-mediated p38MAPK signaling pathway on chronic intermittent hypoxic-induced rat's oxidative stress and inflammatory cytokines in rats.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:1

    Topics: Adipose Tissue; Animals; Antioxidants; Chronic Disease; Cyclic N-Oxides; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Hypoxia; Imidazoles; Male; MAP Kinase Signaling System; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Sleep Apnea, Obstructive; Spin Labels; Toll-Like Receptor 4

2019
The influence of p38 mitogen-activated protein kinase inhibitor on synthesis of inflammatory cytokine tumor necrosis factor alpha in spinal cord of rats with chronic constriction injury.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:6

    Topics: Animals; Chronic Disease; Constriction, Pathologic; Cytokines; Imidazoles; Male; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Spinal Cord; Tumor Necrosis Factor-alpha

2007