sb 203580 has been researched along with Cancer of Lung in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 12 (66.67) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, Y; Jiang, Y; Kang, Y; Li, R; Liu, J; Wang, J | 1 |
| Biswas, S; Chatterjee, S; Das, R; Dey, P; Ghosh, U | 1 |
| Asai, T; Ikari, A; Manabe, A; Matsunaga, T; Onuma, S; Yoshino, Y | 1 |
| Chen, F; Chen, R; Chen, Y; Ding, F; Guo, L; Ma, N; Mei, J; Xiao, H; Zhong, H | 1 |
| Chen, J; Li, JY; Shi, JY; Su, B; Tang, L; Yang, XJ; Zhang, J; Zhao, YM | 1 |
| Gao, FG; Huang, XB; Jiang, YN; Ke, SZ; Li, J; Wang, YN; Yan, HQ; Zhang, YH | 1 |
| Li, ZX; Qiu, XS; Sun, LM; Xia, ZX; Zhang, M; Zhang, QF | 1 |
| Han, YH; Park, WH | 1 |
| Du, Y; Fu, H; Khuri, FR; Li, Z; Liotta, D; Lou, B; Purcell, J; Snyder, JP; Thomas, SL; Zhao, J | 1 |
| Chang, WC; Liao, WL; Tseng, JT; Wang, WC | 1 |
| Bell, AM; Burns, TJ; Matesic, DF; May, SW; Ruch, RJ; Sidorova, TS; Tran, PL | 1 |
| Gu, M; Liang, H; Wang, H; Wen, X; Yang, C; Zhou, Q | 1 |
| Chen, T; Li, H; Qu, J; Wang, X | 1 |
| de Bittencourt Pasquali, MA; Gasparotto, J; Gelain, DP; Moreira, JC; Pires, AS; Terra, SR; Zeidán-Chuliá, F | 1 |
| Harada, R; Kobayashi, M; Nakata, H; Taguchi, H; Uemura, Y | 1 |
| Fan, D; Wei, L; Yang, Y; Yao, L; You, H; Yu, Q; Zhang, X; Zhao, Y | 1 |
| Garcia-Rojas, R; Jackson, RM | 1 |
| Awasthi, V; King, RJ | 1 |
18 other study(ies) available for sb 203580 and Cancer of Lung
| Article | Year |
|---|---|
The anti-tumor activity and mechanism of alkaloids from Aconitum szechenyianum Gay.
Topics: Aconitum; Adenocarcinoma; Adenocarcinoma of Lung; Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Humans; Lung; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Signal Transduction | 2016 |
p38 MAPK inhibitor SB203580 enhances anticancer activity of PARP inhibitor olaparib in a synergistic way on non-small cell lung carcinoma A549 cells.
Topics: A549 Cells; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Phthalazines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Telomerase | 2023 |
Upregulation of Chemoresistance by Mg
Topics: A549 Cells; Adenocarcinoma of Lung; ATP Binding Cassette Transporter, Subfamily B; Cell Cycle; Cell Proliferation; Cisplatin; Cyclosporins; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; Lymph Nodes; Magnesium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reactive Oxygen Species; Roscovitine | 2021 |
Phosphorylation of eIF2α suppresses cisplatin-induced A549 cell apoptosis via p38 inhibition.
Topics: Aged; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cinnamates; Cisplatin; Drug Resistance, Neoplasm; eIF-2 Kinase; Enzyme Activation; Enzyme Inhibitors; Eukaryotic Initiation Factor-2; Female; Humans; Imidazoles; Lung Neoplasms; Male; Middle Aged; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prognosis; Pyridines; Signal Transduction; Thiourea; Tissue Array Analysis | 2013 |
[Small molecule inhibitor SB203580 enhances the antitumor effect of gefitinib in PC-9 and A549 lung cancer cell lines].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Enzyme Inhibitors; Gefitinib; Humans; Imidazoles; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Quinazolines; Signal Transduction | 2013 |
Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activation.
Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; bcl-X Protein; Camptothecin; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Interleukin-6; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Sulfones | 2014 |
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Non-Small-Cell Lung; CARD Signaling Adaptor Proteins; Caspase 3; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; MAP Kinase Signaling System; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription Factor RelA | 2016 |
Treatment with p38 inhibitor partially prevents Calu-6 lung cancer cell death by a proteasome inhibitor, MG132.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Proliferation; Cysteine Proteinase Inhibitors; Flavonoids; Glutathione; Humans; Imidazoles; Leupeptins; Lung Neoplasms; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Tumor Cells, Cultured | 2010 |
Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy.
Topics: Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Cell Line, Tumor; Drug Therapy, Combination; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Piperidones; Pyridines | 2010 |
The RNA-binding protein HuR stabilizes cytosolic phospholipase A2α mRNA under interleukin-1β treatment in non-small cell lung cancer A549 Cells.
Topics: 3' Untranslated Regions; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclooxygenase 2; ELAV Proteins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Group IV Phospholipases A2; Humans; Imidazoles; Inflammation; Interleukin-1beta; Lung Neoplasms; MAP Kinase Signaling System; Mutation; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA Stability; RNA, Neoplasm | 2011 |
p38 MAPK activation, JNK inhibition, neoplastic growth inhibition, and increased gap junction communication in human lung carcinoma and Ras-transformed cells by 4-phenyl-3-butenoic acid.
Topics: Animals; Apoptosis; Cell Communication; Cell Line, Tumor; Cell Proliferation; Connexin 43; Epithelial Cells; Fatty Acids, Monounsaturated; Gap Junctions; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Liver; Lung Neoplasms; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats | 2012 |
Sevoflurane inhibits invasion and migration of lung cancer cells by inactivating the p38 MAPK signaling pathway.
Topics: Anesthetics, Inhalation; Cell Line, Tumor; Cell Movement; Humans; Imidazoles; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase Inhibitors; Methyl Ethers; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sevoflurane | 2012 |
p38 inhibitor SB203580 sensitizes the resveratrol-induced apoptosis in human lung adenocarcinoma (A549) cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Survival; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Stilbenes | 2012 |
Vitamin A (retinol) downregulates the receptor for advanced glycation endproducts (RAGE) by oxidant-dependent activation of p38 MAPK and NF-kB in human lung cancer A549 cells.
Topics: alpha-Tocopherol; Antioxidants; Cell Line, Tumor; Down-Regulation; Humans; Imidazoles; Lung Neoplasms; Mitogen-Activated Protein Kinase 11; Mitogen-Activated Protein Kinase 14; NF-kappa B; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Pyridines; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; RNA, Small Interfering; Signal Transduction; Transcription Factor RelA; Vitamin A | 2013 |
Cyclooxygenase-2 inhibitor NS-398 suppresses cell growth and constitutive production of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells.
Topics: Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Progression; Drug Screening Assays, Antitumor; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-1; Isoenzymes; Lung Neoplasms; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Proteins; NF-kappa B; Nitrobenzenes; Proline; Prostaglandin-Endoperoxide Synthases; Pyridines; Recombinant Proteins; Sulfonamides; Thiocarbamates; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Annexin A5; Apoptosis; Blotting, Western; Carrier Proteins; Caspases; Cell Line, Tumor; Cell Survival; Chromones; Cycloheximide; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Kinetics; Lung Neoplasms; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction | 2004 |
Kinase activity, heat shock protein 27 phosphorylation, and lung epithelial cell glutathione.
Topics: Adenocarcinoma, Papillary; Cell Line, Tumor; Enzyme Inhibitors; Epithelial Cells; Glutathione; Glutathione Disulfide; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Naphthoquinones; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Respiratory Mucosa; Transfection | 2008 |
PKC, p42/p44 MAPK, and p38 MAPK are required for HGF-induced proliferation of H441 cells.
Topics: Adenocarcinoma; Cell Division; Cell Membrane; Cytosol; Enzyme Inhibitors; Flavonoids; Hepatocyte Growth Factor; Humans; Imidazoles; Indoles; Isoenzymes; Kinetics; Lung Neoplasms; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Mitosis; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Tumor Cells, Cultured | 2000 |