Page last updated: 2024-09-05

sb 203580 and Asthma

sb 203580 has been researched along with Asthma in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (43.75)29.6817
2010's8 (50.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Bobis-Wozowicz, S; Madeja, Z; Michalik, M; Nit, K; Paw, M; Ślusarczyk, A; Szychowski, R; Wnuk, D1
Chen-Yu Hsu, A; Guan, X; Guo, Y; Pang, Z; Ran, N; Wang, F; Wang, G; Wang, Z; Yuan, Y; Zheng, R1
Fang, L; Lu, S; Roth, M; Stolz, D; Sun, Q; Tamm, M; Tang, X1
Bae, CH; Kim, YD; Kim, YW; Park, SY; Seo, YJ; Song, SY1
Al-Jahdali, H; Al-Kufaidy, R; Al-Muhsen, S; Alnassar, SA; BaHammam, AS; Halwani, R; Hamid, Q; Pureza, MA; Vazquez-Tello, A1
Bruno, A; Chanez, P; Chiappara, G; Gerbino, S; Gjomarkaj, M; Gras, D; La Guardia, M; Pace, E; Profita, M; Vachier, I1
Ammit, AJ; Ge, Q; Laufer, S; Manetsch, M; Munoz, L; Peifer, C; Ramsay, EE1
Barnes, PJ; Chung, KF; Hakim, A; Ito, K; Kobayashi, Y; Meah, S; Mercado, N; Usmani, OS1
Harris, T; Mackay, GA; Stewart, AG; Xia, YC1
Li, W; Lin, JT; Shu, J; Sun, LC; Zhang, L; Zhou, TL1
Demedts, MG; Dupont, LJ; Vanaudenaerde, BM; Verleden, GM; Wuyts, WA1
Ip, WK; Lam, CW; Li, ML; Tian, YP; Wang, CB; Wong, CK1
Büning, H; Erdmann, E; Humme, S; Koch, A; Lux, M; Müller, K; Raidl, M1
Bracke, M; Coffer, PJ; Koenderman, L; Lammers, JW; van de Graaf, E1
Hallsworth, MP; Hirst, SJ; Lai, D; Moir, LM1
Adcock, IM; Barnes, PJ; Chung, KF; Irusen, E; Matthews, JG; Takahashi, A1

Other Studies

16 other study(ies) available for sb 203580 and Asthma

ArticleYear
SB203580-A Potent p38 MAPK Inhibitor Reduces the Profibrotic Bronchial Fibroblasts Transition Associated with Asthma.
    International journal of molecular sciences, 2021, Nov-26, Volume: 22, Issue:23

    Topics: Adult; Asthma; Bronchi; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Female; Fibroblasts; Humans; Imidazoles; Male; Middle Aged; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction

2021
Combined treatment with SB203580 and dexamethasone suppresses non-typeable Haemophilus influenzae-induced Th17 inflammation response in murine allergic asthma.
    European journal of pharmacology, 2019, Nov-05, Volume: 862

    Topics: Animals; Asthma; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Female; Haemophilus influenzae; Humans; Imidazoles; Inflammation; Lung; Mice; Mucin 5AC; Mucin-5B; Neutrophils; Ovalbumin; p38 Mitogen-Activated Protein Kinases; Pyridines; Respiratory Mucosa; Signal Transduction; Symptom Flare Up; Th17 Cells

2019
TGF-β Upregulated Mitochondria Mass through the SMAD2/3→C/EBPβ→PRMT1 Signal Pathway in Primary Human Lung Fibroblasts.
    Journal of immunology (Baltimore, Md. : 1950), 2019, 01-01, Volume: 202, Issue:1

    Topics: Airway Remodeling; Asthma; Cells, Cultured; Chaperonin 60; Fibroblasts; Humans; Imidazoles; Mitochondria; Naphthalenesulfonates; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein-Arginine N-Methyltransferases; Pyridines; Repressor Proteins; RNA, Small Interfering; Signal Transduction; Smad2 Protein; Smad3 Protein; Steroid Isomerases; Transforming Growth Factor beta; Up-Regulation; Urea

2019
Effect of Onchocerca volvulus chitinase on MUC5B expression in human airway epithelial cells.
    American journal of rhinology & allergy, 2013, Volume: 27, Issue:1

    Topics: Animals; Asthma; Cell Line; Chitinases; Helminth Proteins; Humans; Imidazoles; Mucin-5B; Onchocerca volvulus; p38 Mitogen-Activated Protein Kinases; Pyridines; Respiratory Mucosa; RNA, Messenger; RNA, Small Interfering; Signal Transduction

2013
IL-17 Enhances Chemotaxis of Primary Human B Cells during Asthma.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Adult; Asthma; B-Lymphocytes; Bronchi; Chemokine CXCL13; Chemotaxis; Enzyme Activation; Female; Humans; Imidazoles; Inflammation; Interleukin-17; Interleukin-8; Male; p38 Mitogen-Activated Protein Kinases; Pulmonary Disease, Chronic Obstructive; Pyridines; Receptors, Interleukin; Receptors, Interleukin-17; Th17 Cells

2014
Leptin and leptin receptor expression in asthma.
    The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:2

    Topics: Adult; Androstadienes; Asthma; Bronchi; Cell Line; Cell Proliferation; Chromones; Enzyme Inhibitors; Female; Fluticasone; Humans; Imidazoles; Leptin; Male; Middle Aged; Morpholines; Pyridines; Receptors, Leptin; Recombinant Proteins; Respiratory Mucosa; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2009
Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle.
    European journal of pharmacology, 2010, Jun-10, Volume: 635, Issue:1-3

    Topics: Anti-Inflammatory Agents; Asthma; Cell Line; Gene Expression Regulation; Humans; Imidazoles; Interleukin-6; Interleukin-8; Isoenzymes; Muscle, Smooth; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Respiratory System; RNA, Messenger; Tumor Necrosis Factor-alpha

2010
Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Asthma; Cell Nucleus; Female; Humans; Imidazoles; Interleukin-8; Leukocytes, Mononuclear; Male; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Protein Kinase Inhibitors; Protein Transport; Pyridines; Receptors, Glucocorticoid; Severity of Illness Index; U937 Cells

2012
Secreted factors from human mast cells trigger inflammatory cytokine production by human airway smooth muscle cells.
    International archives of allergy and immunology, 2013, Volume: 160, Issue:1

    Topics: Asthma; Cell Line; Culture Media, Conditioned; Exosomes; Humans; Imidazoles; Immunoglobulin E; Inflammation; Interleukin-6; Interleukin-8; Mast Cells; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrimidines; Receptors, Fc; Respiratory System; RNA, Messenger; src-Family Kinases

2013
[Mechanism of p38 mitogen-activated protein kinase inhibitor SB203580 to glucocorticoid sensitivity].
    Zhonghua yi xue za zhi, 2012, Sep-25, Volume: 92, Issue:36

    Topics: Animals; Asthma; Cell Line, Tumor; Glucocorticoids; HSP90 Heat-Shock Proteins; Humans; Imidazoles; Lung; Male; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Receptors, Glucocorticoid; Signal Transduction; Smoke

2012
Involvement of p38 MAPK, JNK, p42/p44 ERK and NF-kappaB in IL-1beta-induced chemokine release in human airway smooth muscle cells.
    Respiratory medicine, 2003, Volume: 97, Issue:7

    Topics: Asthma; Blotting, Northern; Butadienes; Cells, Cultured; Chemokine CCL11; Chemokine CCL2; Chemokine CCL7; Chemokines; Chemokines, CC; Curcumin; Cytokines; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Immunoblotting; Interleukin-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monocyte Chemoattractant Proteins; Muscle, Smooth; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrrolidines; Stimulation, Chemical; Thiocarbamates

2003
House dust mite allergen Der p 1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells.
    International immunology, 2006, Volume: 18, Issue:8

    Topics: Antigens, Dermatophagoides; Arthropod Proteins; Asthma; Bronchi; Cell Adhesion Molecules; Coculture Techniques; Curcumin; Cysteine Endopeptidases; Cytokines; Dermatophagoides pteronyssinus; Enzyme Activation; Eosinophils; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyroglyphidae; Sulfones; Th2 Cells; Transcription Factor AP-1

2006
IL-12-induced T-bet expression and IFNgamma release in lymphocytes from asthmatics--role of MAPkinases ERK-1/-2, p38(MAPK) and effect of dexamethasone.
    Respiratory medicine, 2007, Volume: 101, Issue:6

    Topics: Adult; Asthma; Cells, Cultured; Dexamethasone; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Flavonoids; Gene Expression Regulation; Glucocorticoids; Humans; Imidazoles; Interferon-gamma; Interleukin-12; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Box Domain Proteins; T-Lymphocytes

2007
In vivo priming of FcalphaR functioning on eosinophils of allergic asthmatics.
    Journal of leukocyte biology, 2000, Volume: 68, Issue:5

    Topics: Adolescent; Adult; Antigens, CD; Asthma; Chromones; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Female; Humans; Imidazoles; Immunoglobulin A; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Receptors, Fc; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Signal Transduction; Tumor Necrosis Factor-alpha

2000
Inhibitors of mitogen-activated protein kinases differentially regulate eosinophil-activating cytokine release from human airway smooth muscle.
    American journal of respiratory and critical care medicine, 2001, Aug-15, Volume: 164, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchi; Butadienes; Cytokines; Drug Evaluation, Preclinical; Eosinophils; Female; Flavonoids; Humans; Imidazoles; Lung Diseases, Obstructive; Male; MAP Kinase Kinase Kinase 1; Middle Aged; Mitogen-Activated Protein Kinases; Muscle, Smooth; Nitriles; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Up-Regulation

2001
p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma.
    The Journal of allergy and clinical immunology, 2002, Volume: 109, Issue:4

    Topics: Administration, Oral; Adult; Asthma; Drug Resistance; Female; Forced Expiratory Volume; Glucocorticoids; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-10; Interleukin-2; Interleukin-4; Male; Middle Aged; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Glucocorticoid

2002