sb 202190 has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 2 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute lymphoblastic leukemia (ALL) is the most common hematological malignancy affecting children." | 1.34 | Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy. ( Barredo, JC; Hsieh-Kinser, TT; Leclerc, GJ; Leclerc, GM; Sengupta, TK; Singh, I, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen-Deutsch, X | 1 |
| Garay, E | 1 |
| Zhang, J | 1 |
| Harrison, JS | 1 |
| Studzinski, GP | 1 |
| Sengupta, TK | 1 |
| Leclerc, GM | 1 |
| Hsieh-Kinser, TT | 1 |
| Leclerc, GJ | 1 |
| Singh, I | 1 |
| Barredo, JC | 1 |
2 other studies available for sb 202190 and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
c-Jun N-terminal kinase 2 (JNK2) antagonizes the signaling of differentiation by JNK1 in human myeloid leukemia cells resistant to vitamin D.
Topics: Abietanes; Antioxidants; Cell Differentiation; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhi | 2009 |
Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Cell Di | 2007 |