sb 202190 has been researched along with Pancreatic Neoplasms in 4 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of pancreatic cancer cells with CC-8075 and CC-8062 reduces their proliferation and increases apoptosis that is caspase dependent in T3M4 cells." | 1.35 | Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells. ( Bartlett, JB; Colston, KW; Dalgleish, AG; Man, HW; Mouratidis, PX; Muller, GW; Stirling, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malm, SW | 1 |
| Hanke, NT | 1 |
| Gill, A | 1 |
| Carbajal, L | 1 |
| Baker, AF | 1 |
| Mouratidis, PX | 1 |
| Colston, KW | 1 |
| Bartlett, JB | 1 |
| Muller, GW | 1 |
| Man, HW | 1 |
| Stirling, D | 1 |
| Dalgleish, AG | 1 |
| Emonds, E | 1 |
| Fitzner, B | 1 |
| Jaster, R | 1 |
| Watanabe, S | 1 |
| Kishimoto, T | 1 |
| Yokosuka, O | 1 |
4 other studies available for sb 202190 and Pancreatic Neoplasms
| Article | Year |
|---|---|
The anti-tumor efficacy of 2-deoxyglucose and D-allose are enhanced with p38 inhibition in pancreatic and ovarian cell lines.
Topics: Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Dose-Respon | 2015 |
Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells.
Topics: Alitretinoin; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclic Nucleot | 2009 |
Molecular determinants of the antitumor effects of trichostatin A in pancreatic cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Gene Expr | 2010 |
Hepatocyte growth factor inhibits anoikis of pancreatic carcinoma cells through phosphatidylinositol 3-kinase pathway.
Topics: Androstadienes; Animals; Anoikis; Antibodies; Blotting, Western; Cadherins; Cell Adhesion; Cell Comm | 2011 |