sb 202190 has been researched along with Ovarian Neoplasms in 4 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicotine treatment reduced SKOV3 and TOV112D spheroid invasion and compaction but did not significantly affect spheroid formation." | 1.56 | Nicotine inhibits MAPK signaling and spheroid invasion in ovarian cancer cells. ( Bouni, ME; Chadee, DN; Harmych, SJ; Kumar, J, 2020) |
| "Many targeted ovarian cancer patients are resistant to olaparib treatment." | 1.48 | The Drug Combination of SB202190 and SP600125 Significantly Inhibit the Growth and Metastasis of Olaparib-resistant Ovarian Cancer Cell. ( Chen, X; Chen, Y; Hou, X; Lin, X; Su, S; Tian, Y; Zhang, Q, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harmych, SJ | 1 |
| Kumar, J | 1 |
| Bouni, ME | 1 |
| Chadee, DN | 1 |
| Chen, X | 1 |
| Chen, Y | 1 |
| Lin, X | 1 |
| Su, S | 1 |
| Hou, X | 1 |
| Zhang, Q | 1 |
| Tian, Y | 1 |
| Malm, SW | 1 |
| Hanke, NT | 1 |
| Gill, A | 1 |
| Carbajal, L | 1 |
| Baker, AF | 1 |
| Quan, H | 1 |
| Xu, Y | 1 |
| Lou, L | 1 |
4 other studies available for sb 202190 and Ovarian Neoplasms
| Article | Year |
|---|---|
Nicotine inhibits MAPK signaling and spheroid invasion in ovarian cancer cells.
Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Female; Humans; Imidazoles; Nic | 2020 |
The Drug Combination of SB202190 and SP600125 Significantly Inhibit the Growth and Metastasis of Olaparib-resistant Ovarian Cancer Cell.
Topics: Animals; Anthracenes; Autophagy; Cell Line, Tumor; Cell Proliferation; Drug Combinations; Female; Hu | 2018 |
The anti-tumor efficacy of 2-deoxyglucose and D-allose are enhanced with p38 inhibition in pancreatic and ovarian cell lines.
Topics: Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Dose-Respon | 2015 |
p38 MAPK, but not ERK1/2, is critically involved in the cytotoxicity of the novel vascular disrupting agent combretastatin A4.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinoma, Hepatocell | 2008 |