sb 202190 has been researched along with Osteoarthritis, Knee in 1 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manacu, CA | 1 |
| Martel-Pelletier, J | 1 |
| Roy-Beaudry, M | 1 |
| Pelletier, JP | 1 |
| Fernandes, JC | 1 |
| Shipkolye, FS | 1 |
| Mitrovic, DR | 1 |
| Moldovan, F | 1 |
1 other study available for sb 202190 and Osteoarthritis, Knee
| Article | Year |
|---|---|
Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production.
Topics: Aminoquinolines; Apoptosis; Carbazoles; Cartilage, Articular; Cells, Cultured; Chondrocytes; Collage | 2005 |