sb 202190 has been researched along with Necrosis in 6 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Necrosis was assessed after 40 min of ischemia and 2 h of reperfusion using 2,3,5-triphenyltetrazolium chloride (TTC) staining and creatine kinase release." | 1.31 | Inhibition of p38 MAPK alpha/beta reduces ischemic injury and does not block protective effects of preconditioning. ( Chen, W; Hou, J; Murphy, E; Schneider, S; Steenbergen, C, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Felipe, KB | 1 |
| Benites, J | 1 |
| Glorieux, C | 1 |
| Sid, B | 1 |
| Valenzuela, M | 1 |
| Kviecinski, MR | 1 |
| Pedrosa, RC | 1 |
| Valderrama, JA | 1 |
| Levêque, P | 1 |
| Gallez, B | 1 |
| Verrax, J | 1 |
| Buc Calderon, P | 1 |
| Chen, KC | 1 |
| Kao, PH | 1 |
| Lin, SR | 1 |
| Chang, LS | 1 |
| Park, JM | 1 |
| Greten, FR | 1 |
| Li, ZW | 1 |
| Karin, M | 1 |
| Scheller, C | 1 |
| Sopper, S | 1 |
| Ehrhardt, C | 1 |
| Flory, E | 1 |
| Chen, P | 1 |
| Koutsilieri, E | 1 |
| Ludwig, S | 1 |
| ter Meulen, V | 1 |
| Jassoy, C | 1 |
| Oh, HM | 1 |
| Choi, SC | 1 |
| Lee, HS | 1 |
| Chun, CH | 1 |
| Seo, GS | 1 |
| Choi, EY | 1 |
| Lee, HJ | 1 |
| Lee, MS | 1 |
| Yeom, JJ | 1 |
| Choi, SJ | 1 |
| Han, WC | 1 |
| Oh, JM | 1 |
| Chung, YT | 1 |
| Chun, JS | 1 |
| Lee, KM | 1 |
| Jun, CD | 1 |
| Schneider, S | 1 |
| Chen, W | 1 |
| Hou, J | 1 |
| Steenbergen, C | 1 |
| Murphy, E | 1 |
6 other studies available for sb 202190 and Necrosis
| Article | Year |
|---|---|
Antiproliferative effects of phenylaminonaphthoquinones are increased by ascorbate and associated with the appearance of a senescent phenotype in human bladder cancer cells.
Topics: Aminophenols; Aniline Compounds; Antineoplastic Agents; Ascorbic Acid; Caspase 3; Cell Cycle Checkpo | 2013 |
p38 MAPK activation and mitochondrial depolarization mediate the cytotoxicity of Taiwan cobra phospholipase A2 on human neuroblastoma SK-N-SH cells.
Topics: Animals; Cell Line, Tumor; Cell Survival; Cytochromes c; Elapid Venoms; Elapidae; Enzyme Inhibitors; | 2008 |
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition.
Topics: Animals; Antigens, Bacterial; Apoptosis; Bacterial Toxins; Calcium-Calmodulin-Dependent Protein Kina | 2002 |
Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes.
Topics: Amino Acid Chloromethyl Ketones; Antigens, CD; Apoptosis; Butadienes; Cell Line; Cysteine Endopeptid | 2002 |
Combined action of extracellular signal-regulated kinase and p38 kinase rescues Molt4 T cells from nitric oxide-induced apoptotic and necrotic cell death.
Topics: Apoptosis; Blotting, Western; Carcinogens; Caspase 3; Caspase 8; Caspases; Catalysis; Cell Line, Tum | 2004 |
Inhibition of p38 MAPK alpha/beta reduces ischemic injury and does not block protective effects of preconditioning.
Topics: Animals; Enzyme Inhibitors; Glycolysis; Heart Rate; Hydrogen-Ion Concentration; Imidazoles; Ischemic | 2001 |