Page last updated: 2024-11-04

sb 202190 and Necrosis

sb 202190 has been researched along with Necrosis in 6 studies

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Necrosis was assessed after 40 min of ischemia and 2 h of reperfusion using 2,3,5-triphenyltetrazolium chloride (TTC) staining and creatine kinase release."1.31Inhibition of p38 MAPK alpha/beta reduces ischemic injury and does not block protective effects of preconditioning. ( Chen, W; Hou, J; Murphy, E; Schneider, S; Steenbergen, C, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Felipe, KB1
Benites, J1
Glorieux, C1
Sid, B1
Valenzuela, M1
Kviecinski, MR1
Pedrosa, RC1
Valderrama, JA1
Levêque, P1
Gallez, B1
Verrax, J1
Buc Calderon, P1
Chen, KC1
Kao, PH1
Lin, SR1
Chang, LS1
Park, JM1
Greten, FR1
Li, ZW1
Karin, M1
Scheller, C1
Sopper, S1
Ehrhardt, C1
Flory, E1
Chen, P1
Koutsilieri, E1
Ludwig, S1
ter Meulen, V1
Jassoy, C1
Oh, HM1
Choi, SC1
Lee, HS1
Chun, CH1
Seo, GS1
Choi, EY1
Lee, HJ1
Lee, MS1
Yeom, JJ1
Choi, SJ1
Han, WC1
Oh, JM1
Chung, YT1
Chun, JS1
Lee, KM1
Jun, CD1
Schneider, S1
Chen, W1
Hou, J1
Steenbergen, C1
Murphy, E1

Other Studies

6 other studies available for sb 202190 and Necrosis

ArticleYear
Antiproliferative effects of phenylaminonaphthoquinones are increased by ascorbate and associated with the appearance of a senescent phenotype in human bladder cancer cells.
    Biochemical and biophysical research communications, 2013, Apr-19, Volume: 433, Issue:4

    Topics: Aminophenols; Aniline Compounds; Antineoplastic Agents; Ascorbic Acid; Caspase 3; Cell Cycle Checkpo

2013
p38 MAPK activation and mitochondrial depolarization mediate the cytotoxicity of Taiwan cobra phospholipase A2 on human neuroblastoma SK-N-SH cells.
    Toxicology letters, 2008, Jul-30, Volume: 180, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Survival; Cytochromes c; Elapid Venoms; Elapidae; Enzyme Inhibitors;

2008
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition.
    Science (New York, N.Y.), 2002, Sep-20, Volume: 297, Issue:5589

    Topics: Animals; Antigens, Bacterial; Apoptosis; Bacterial Toxins; Calcium-Calmodulin-Dependent Protein Kina

2002
Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes.
    European journal of immunology, 2002, Volume: 32, Issue:9

    Topics: Amino Acid Chloromethyl Ketones; Antigens, CD; Apoptosis; Butadienes; Cell Line; Cysteine Endopeptid

2002
Combined action of extracellular signal-regulated kinase and p38 kinase rescues Molt4 T cells from nitric oxide-induced apoptotic and necrotic cell death.
    Free radical biology & medicine, 2004, Aug-15, Volume: 37, Issue:4

    Topics: Apoptosis; Blotting, Western; Carcinogens; Caspase 3; Caspase 8; Caspases; Catalysis; Cell Line, Tum

2004
Inhibition of p38 MAPK alpha/beta reduces ischemic injury and does not block protective effects of preconditioning.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:2

    Topics: Animals; Enzyme Inhibitors; Glycolysis; Heart Rate; Hydrogen-Ion Concentration; Imidazoles; Ischemic

2001