sb 202190 has been researched along with Lung Neoplasms in 14 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously found that p300 mediates cancer-induced muscle wasting by activating C/EBPβ, which then upregulates key catabolic genes." | 1.62 | Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300. ( Frost, JA; Li, M; Li, YP; Sin, TK; Zhang, G; Zhang, Z; Zhu, JZ; Zuo, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Sin, TK | 1 |
| Zhang, G | 2 |
| Zhang, Z | 1 |
| Zhu, JZ | 1 |
| Zuo, Y | 1 |
| Frost, JA | 1 |
| Li, M | 1 |
| Li, YP | 2 |
| Ko, JC | 1 |
| Chiu, HC | 2 |
| Wo, TY | 2 |
| Huang, YJ | 2 |
| Tseng, SC | 3 |
| Huang, YC | 2 |
| Chen, HJ | 2 |
| Syu, JJ | 2 |
| Chen, CY | 2 |
| Jian, YT | 2 |
| Jian, YJ | 2 |
| Lin, YW | 3 |
| Tung, CL | 1 |
| Sunaga, N | 1 |
| Imai, H | 1 |
| Shimizu, K | 1 |
| Shames, DS | 1 |
| Kakegawa, S | 1 |
| Girard, L | 1 |
| Sato, M | 1 |
| Kaira, K | 1 |
| Ishizuka, T | 1 |
| Gazdar, AF | 1 |
| Minna, JD | 1 |
| Mori, M | 1 |
| Jin, B | 1 |
| Tsai, MS | 1 |
| Weng, SH | 1 |
| Chiu, YF | 1 |
| Kuo, YH | 1 |
| Kim, HA | 1 |
| Kim, KJ | 1 |
| Seo, KH | 1 |
| Lee, HK | 1 |
| Im, SY | 1 |
| Yeh, FT | 1 |
| Wu, CH | 1 |
| Lee, HZ | 1 |
| Chao, JI | 1 |
| Kuo, PC | 1 |
| Hsu, TS | 1 |
| Niiya, M | 1 |
| Niiya, K | 1 |
| Shibakura, M | 1 |
| Asaumi, N | 1 |
| Yoshida, C | 1 |
| Shinagawa, K | 1 |
| Teshima, T | 1 |
| Ishimaru, F | 1 |
| Ikeda, K | 1 |
| Tanimoto, M | 1 |
| Lee, HY | 1 |
| Oh, SH | 1 |
| Suh, YA | 1 |
| Baek, JH | 1 |
| Papadimitrakopoulou, V | 1 |
| Huang, S | 1 |
| Hong, WK | 1 |
| Alam, M | 1 |
| Wang, JH | 1 |
| Coffey, JC | 1 |
| Qadri, SS | 1 |
| O'Donnell, A | 1 |
| Aherne, T | 1 |
| Redmond, HP | 1 |
| Mu, D | 1 |
| Zhang, W | 1 |
| Chu, D | 1 |
| Liu, T | 1 |
| Xie, Y | 1 |
| Fu, E | 1 |
| Jin, F | 1 |
| Chuang, SM | 1 |
| Liou, GY | 1 |
| Yang, JL | 1 |
14 other studies available for sb 202190 and Lung Neoplasms
| Article | Year |
|---|---|
Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300.
Topics: Animals; Cachexia; Carcinoma, Lewis Lung; Cells, Cultured; Humans; Imidazoles; Lung Neoplasms; Male; | 2021 |
Inhibition of p38 MAPK-dependent MutS homologue-2 (MSH2) expression by metformin enhances gefitinib-induced cytotoxicity in human squamous lung cancer cells.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemotherapy, Adjuvan | 2013 |
Down-regulation of MSH2 expression by an Hsp90 inhibitor enhances pemetrexed-induced cytotoxicity in human non-small-cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Proliferat | 2014 |
Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer.
Topics: Aged; Butadienes; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Cell Movement; Cell P | 2012 |
C/EBPβ mediates tumour-induced ubiquitin ligase atrogin1/MAFbx upregulation and muscle wasting.
Topics: Animals; Cachexia; Carcinoma, Lewis Lung; Cell Line; Enzyme Inhibitors; Forkhead Box Protein O1; For | 2011 |
Inhibition of p38 MAPK-dependent excision repair cross-complementing 1 expression decreases the DNA repair capacity to sensitize lung cancer cells to etoposide.
Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Blotting, Western; Carcinoma, Non-Small-Cell Lung; | 2012 |
PTEN/MAPK pathways play a key role in platelet-activating factor-induced experimental pulmonary tumor metastasis.
Topics: Androstadienes; Animals; Anthracenes; Butadienes; Cell Line; Humans; Imidazoles; Lung Neoplasms; MAP | 2012 |
Signaling pathway for aloe-emodin-induced apoptosis in human H460 lung nonsmall carcinoma cell.
Topics: Alkaloids; Anthraquinones; Apoptosis; Benzophenanthridines; Blotting, Western; Carcinoma, Non-Small- | 2003 |
Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Arsenites; Benzazepines; Blotting, Western; Carcinoma; CDC2 Protei | 2004 |
Involvement of ERK1/2 and p38 MAP kinase in doxorubicin-induced uPA expression in human RC-K8 lymphoma and NCI-H69 small cell lung carcinoma cells.
Topics: Blotting, Northern; Blotting, Western; Butadienes; Carcinoma, Small Cell; Caspase 3; Caspases; Cell | 2004 |
Response of non-small cell lung cancer cells to the inhibitors of phosphatidylinositol 3-kinase/Akt- and MAPK kinase 4/c-Jun NH2-terminal kinase pathways: an effective therapeutic strategy for lung cancer.
Topics: Adenoviridae; Animals; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspase 3; Casp | 2005 |
Characterization of the effects of cyclooxygenase-2 inhibition in the regulation of apoptosis in human small and non-small cell lung cancer cell lines.
Topics: Analysis of Variance; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small | 2007 |
The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.
Topics: Antimalarials; Apoptosis; Artemisinins; Blotting, Western; Calcium; Cell Line, Tumor; Chelating Agen | 2008 |
Activation of JNK, p38 and ERK mitogen-activated protein kinases by chromium(VI) is mediated through oxidative stress but does not affect cytotoxicity.
Topics: Adenocarcinoma; Amitrole; Catalase; Cell Division; Chelating Agents; Chromates; Drug Interactions; E | 2000 |