sb 202190 has been researched along with Leukemia in 3 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirosawa, M | 1 |
| Nakahara, M | 1 |
| Otosaka, R | 1 |
| Imoto, A | 1 |
| Okazaki, T | 1 |
| Takahashi, S | 1 |
| Chen, Y | 1 |
| Zhao, Y | 1 |
| Wang, C | 1 |
| Xiao, X | 1 |
| Zhou, X | 1 |
| Xu, G | 1 |
| Jacquel, A | 1 |
| Herrant, M | 1 |
| Defamie, V | 1 |
| Belhacene, N | 1 |
| Colosetti, P | 1 |
| Marchetti, S | 1 |
| Legros, L | 1 |
| Deckert, M | 1 |
| Mari, B | 1 |
| Cassuto, JP | 1 |
| Hofman, P | 1 |
| Auberger, P | 1 |
3 other studies available for sb 202190 and Leukemia
| Article | Year |
|---|---|
The p38 pathway inhibitor SB202190 activates MEK/MAPK to stimulate the growth of leukemia cells.
Topics: Base Sequence; Cell Division; Cell Line, Tumor; DNA Primers; Enzyme Activation; Humans; Imidazoles; | 2009 |
Inhibition of p38 MAPK diminishes doxorubicin-induced drug resistance associated with P-glycoprotein in human leukemia K562 cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Dose-Response Relationship, | 2012 |
A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.
Topics: Base Sequence; Cell Differentiation; DNA Primers; DNA, Complementary; Enzyme Inhibitors; Humans; Imi | 2006 |