sb 202190 has been researched along with Leukemia, Myeloid, Acute in 4 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 3 (75.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chen-Deutsch, X | 2 |
Garay, E | 1 |
Zhang, J | 2 |
Harrison, JS | 2 |
Studzinski, GP | 4 |
Thompson, T | 1 |
Danilenko, M | 1 |
Vassilev, L | 1 |
4 other studies available for sb 202190 and Leukemia, Myeloid, Acute
Article | Year |
---|---|
c-Jun N-terminal kinase 2 (JNK2) antagonizes the signaling of differentiation by JNK1 in human myeloid leukemia cells resistant to vitamin D.
Topics: Abietanes; Antioxidants; Cell Differentiation; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhi | 2009 |
Tumor suppressor p53 status does not determine the differentiation-associated G₁ cell cycle arrest induced in leukemia cells by 1,25-dihydroxyvitamin D₃ and antioxidants.
Topics: Abietanes; Antioxidants; Apoptosis; Blotting, Western; Calcitriol; Cell Cycle; Cell Line, Tumor; Cyc | 2010 |
Isoforms of p38MAPK gamma and delta contribute to differentiation of human AML cells induced by 1,25-dihydroxyvitamin D₃.
Topics: Antigens, Differentiation; Calcitriol; Cell Differentiation; Dose-Response Relationship, Drug; Gene | 2011 |
Dual role of hematopoietic progenitor kinase 1 (HPK1) as a positive regulator of 1α,25-dihydroxyvitamin D-induced differentiation and cell cycle arrest of AML cells and as a mediator of vitamin D resistance.
Topics: Abietanes; Amino Acid Chloromethyl Ketones; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, | 2012 |