Compounds > sb 202190
Page last updated: 2024-11-04

sb 202190 and Leukemia, Myeloid, Acute

sb 202190 has been researched along with Leukemia, Myeloid, Acute in 4 studies

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen-Deutsch, X2
Garay, E1
Zhang, J2
Harrison, JS2
Studzinski, GP4
Thompson, T1
Danilenko, M1
Vassilev, L1

Other Studies

4 other studies available for sb 202190 and Leukemia, Myeloid, Acute

ArticleYear
c-Jun N-terminal kinase 2 (JNK2) antagonizes the signaling of differentiation by JNK1 in human myeloid leukemia cells resistant to vitamin D.
    Leukemia research, 2009, Volume: 33, Issue:10

    Topics: Abietanes; Antioxidants; Cell Differentiation; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhi

2009
Tumor suppressor p53 status does not determine the differentiation-associated G₁ cell cycle arrest induced in leukemia cells by 1,25-dihydroxyvitamin D₃ and antioxidants.
    Cancer biology & therapy, 2010, Aug-15, Volume: 10, Issue:4

    Topics: Abietanes; Antioxidants; Apoptosis; Blotting, Western; Calcitriol; Cell Cycle; Cell Line, Tumor; Cyc

2010
Isoforms of p38MAPK gamma and delta contribute to differentiation of human AML cells induced by 1,25-dihydroxyvitamin D₃.
    Experimental cell research, 2011, Jan-01, Volume: 317, Issue:1

    Topics: Antigens, Differentiation; Calcitriol; Cell Differentiation; Dose-Response Relationship, Drug; Gene

2011
Dual role of hematopoietic progenitor kinase 1 (HPK1) as a positive regulator of 1α,25-dihydroxyvitamin D-induced differentiation and cell cycle arrest of AML cells and as a mediator of vitamin D resistance.
    Cell cycle (Georgetown, Tex.), 2012, Apr-01, Volume: 11, Issue:7

    Topics: Abietanes; Amino Acid Chloromethyl Ketones; Cell Cycle Checkpoints; Cell Differentiation; Cell Line,

2012