sb 202190 has been researched along with Carcinoma, Lewis Lung in 3 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously found that p300 mediates cancer-induced muscle wasting by activating C/EBPβ, which then upregulates key catabolic genes." | 1.62 | Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300. ( Frost, JA; Li, M; Li, YP; Sin, TK; Zhang, G; Zhang, Z; Zhu, JZ; Zuo, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sin, TK | 1 |
| Zhang, G | 3 |
| Zhang, Z | 1 |
| Zhu, JZ | 1 |
| Zuo, Y | 1 |
| Frost, JA | 1 |
| Li, M | 1 |
| Li, YP | 3 |
| Lin, RK | 1 |
| Kwon, YT | 1 |
| Jin, B | 1 |
3 other studies available for sb 202190 and Carcinoma, Lewis Lung
| Article | Year |
|---|---|
Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300.
Topics: Animals; Cachexia; Carcinoma, Lewis Lung; Cells, Cultured; Humans; Imidazoles; Lung Neoplasms; Male; | 2021 |
Signaling mechanism of tumor cell-induced up-regulation of E3 ubiquitin ligase UBR2.
Topics: Animals; Blotting, Western; Carcinoma, Lewis Lung; CCAAT-Enhancer-Binding Protein-beta; Cell Line; C | 2013 |
C/EBPβ mediates tumour-induced ubiquitin ligase atrogin1/MAFbx upregulation and muscle wasting.
Topics: Animals; Cachexia; Carcinoma, Lewis Lung; Cell Line; Enzyme Inhibitors; Forkhead Box Protein O1; For | 2011 |