sb 202190 has been researched along with Cancer of Prostate in 4 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
Excerpt | Relevance | Reference |
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"Moreover, prostate cancer cells with a predominantly osteolytic phenotype produced sufficient amounts of DKK-1 to inhibit Wnt3a-induced osteoblastic differentiation in C2C12 cells." | 1.43 | p38 MAPK regulates the Wnt inhibitor Dickkopf-1 in osteotropic prostate cancer cells. ( Browne, AJ; Göbel, A; Hofbauer, LC; Rachner, TD; Rauner, M; Thiele, S, 2016) |
"Expression of p75(NTR) is lost as prostate cancer progresses and is minimal in several metastatic prostate cancer cell lines." | 1.36 | NSAID inhibition of prostate cancer cell migration is mediated by Nag-1 Induction via the p38 MAPK-p75(NTR) pathway. ( Djakiew, D; Wynne, S, 2010) |
"Interleukin-6 (IL-6) induces prostate cancer (CaP) cell proliferation in vitro." | 1.31 | Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression. ( Keller, ET; Lin, DL; Whitney, MC; Yao, Z, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Browne, AJ | 1 |
Göbel, A | 1 |
Thiele, S | 1 |
Hofbauer, LC | 1 |
Rauner, M | 1 |
Rachner, TD | 1 |
Wynne, S | 1 |
Djakiew, D | 1 |
Lin, DL | 1 |
Whitney, MC | 1 |
Yao, Z | 1 |
Keller, ET | 1 |
Mehta, PB | 1 |
Robson, CN | 1 |
Neal, DE | 1 |
Leung, HY | 1 |
4 other studies available for sb 202190 and Cancer of Prostate
Article | Year |
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p38 MAPK regulates the Wnt inhibitor Dickkopf-1 in osteotropic prostate cancer cells.
Topics: Antibodies, Neutralizing; Cell Differentiation; Cell Line, Tumor; Down-Regulation; Humans; Imidazole | 2016 |
NSAID inhibition of prostate cancer cell migration is mediated by Nag-1 Induction via the p38 MAPK-p75(NTR) pathway.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Movement; Flurbiprofen; Growth Diffe | 2010 |
Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression.
Topics: Anilides; Blotting, Western; Cell Nucleus; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flav | 2001 |
Keratinocyte growth factor activates p38 MAPK to induce stress fibre formation in human prostate DU145 cells.
Topics: Animals; Butadienes; COS Cells; Enzyme Inhibitors; Fibroblast Growth Factor 7; Fibroblast Growth Fac | 2001 |