Page last updated: 2024-11-04

sb 202190 and Cancer of Prostate

sb 202190 has been researched along with Cancer of Prostate in 4 studies

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase

Research Excerpts

ExcerptRelevanceReference
"Moreover, prostate cancer cells with a predominantly osteolytic phenotype produced sufficient amounts of DKK-1 to inhibit Wnt3a-induced osteoblastic differentiation in C2C12 cells."1.43p38 MAPK regulates the Wnt inhibitor Dickkopf-1 in osteotropic prostate cancer cells. ( Browne, AJ; Göbel, A; Hofbauer, LC; Rachner, TD; Rauner, M; Thiele, S, 2016)
"Expression of p75(NTR) is lost as prostate cancer progresses and is minimal in several metastatic prostate cancer cell lines."1.36NSAID inhibition of prostate cancer cell migration is mediated by Nag-1 Induction via the p38 MAPK-p75(NTR) pathway. ( Djakiew, D; Wynne, S, 2010)
"Interleukin-6 (IL-6) induces prostate cancer (CaP) cell proliferation in vitro."1.31Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression. ( Keller, ET; Lin, DL; Whitney, MC; Yao, Z, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Browne, AJ1
Göbel, A1
Thiele, S1
Hofbauer, LC1
Rauner, M1
Rachner, TD1
Wynne, S1
Djakiew, D1
Lin, DL1
Whitney, MC1
Yao, Z1
Keller, ET1
Mehta, PB1
Robson, CN1
Neal, DE1
Leung, HY1

Other Studies

4 other studies available for sb 202190 and Cancer of Prostate

ArticleYear
p38 MAPK regulates the Wnt inhibitor Dickkopf-1 in osteotropic prostate cancer cells.
    Cell death & disease, 2016, Feb-25, Volume: 7

    Topics: Antibodies, Neutralizing; Cell Differentiation; Cell Line, Tumor; Down-Regulation; Humans; Imidazole

2016
NSAID inhibition of prostate cancer cell migration is mediated by Nag-1 Induction via the p38 MAPK-p75(NTR) pathway.
    Molecular cancer research : MCR, 2010, Volume: 8, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Movement; Flurbiprofen; Growth Diffe

2010
Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:6

    Topics: Anilides; Blotting, Western; Cell Nucleus; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flav

2001
Keratinocyte growth factor activates p38 MAPK to induce stress fibre formation in human prostate DU145 cells.
    Oncogene, 2001, Aug-30, Volume: 20, Issue:38

    Topics: Animals; Butadienes; COS Cells; Enzyme Inhibitors; Fibroblast Growth Factor 7; Fibroblast Growth Fac

2001