sb 202190 has been researched along with Cancer of Ovary in 4 studies
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicotine treatment reduced SKOV3 and TOV112D spheroid invasion and compaction but did not significantly affect spheroid formation." | 1.56 | Nicotine inhibits MAPK signaling and spheroid invasion in ovarian cancer cells. ( Bouni, ME; Chadee, DN; Harmych, SJ; Kumar, J, 2020) |
| "Many targeted ovarian cancer patients are resistant to olaparib treatment." | 1.48 | The Drug Combination of SB202190 and SP600125 Significantly Inhibit the Growth and Metastasis of Olaparib-resistant Ovarian Cancer Cell. ( Chen, X; Chen, Y; Hou, X; Lin, X; Su, S; Tian, Y; Zhang, Q, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harmych, SJ | 1 |
| Kumar, J | 1 |
| Bouni, ME | 1 |
| Chadee, DN | 1 |
| Chen, X | 1 |
| Chen, Y | 1 |
| Lin, X | 1 |
| Su, S | 1 |
| Hou, X | 1 |
| Zhang, Q | 1 |
| Tian, Y | 1 |
| Malm, SW | 1 |
| Hanke, NT | 1 |
| Gill, A | 1 |
| Carbajal, L | 1 |
| Baker, AF | 1 |
| Quan, H | 1 |
| Xu, Y | 1 |
| Lou, L | 1 |
4 other studies available for sb 202190 and Cancer of Ovary
| Article | Year |
|---|---|
Nicotine inhibits MAPK signaling and spheroid invasion in ovarian cancer cells.
Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Female; Humans; Imidazoles; Nic | 2020 |
The Drug Combination of SB202190 and SP600125 Significantly Inhibit the Growth and Metastasis of Olaparib-resistant Ovarian Cancer Cell.
Topics: Animals; Anthracenes; Autophagy; Cell Line, Tumor; Cell Proliferation; Drug Combinations; Female; Hu | 2018 |
The anti-tumor efficacy of 2-deoxyglucose and D-allose are enhanced with p38 inhibition in pancreatic and ovarian cell lines.
Topics: Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Dose-Respon | 2015 |
p38 MAPK, but not ERK1/2, is critically involved in the cytotoxicity of the novel vascular disrupting agent combretastatin A4.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinoma, Hepatocell | 2008 |