Page last updated: 2024-11-04

sb 202190 and Cachexia

sb 202190 has been researched along with Cachexia in 3 studies

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase

Cachexia: General ill health, malnutrition, and weight loss, usually associated with chronic disease.

Research Excerpts

ExcerptRelevanceReference
"We previously found that p300 mediates cancer-induced muscle wasting by activating C/EBPβ, which then upregulates key catabolic genes."1.62Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300. ( Frost, JA; Li, M; Li, YP; Sin, TK; Zhang, G; Zhang, Z; Zhu, JZ; Zuo, Y, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Sin, TK1
Zhang, G2
Zhang, Z1
Zhu, JZ1
Zuo, Y1
Frost, JA1
Li, M1
Li, YP2
McClung, JM1
Judge, AR1
Powers, SK1
Yan, Z1
Jin, B1

Other Studies

3 other studies available for sb 202190 and Cachexia

ArticleYear
Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300.
    Cancer research, 2021, 02-15, Volume: 81, Issue:4

    Topics: Animals; Cachexia; Carcinoma, Lewis Lung; Cells, Cultured; Humans; Imidazoles; Lung Neoplasms; Male;

2021
p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting.
    American journal of physiology. Cell physiology, 2010, Volume: 298, Issue:3

    Topics: Aldehydes; Animals; Autophagy; Cachexia; Cell Line; Dexamethasone; Enzyme Activation; Forkhead Box P

2010
C/EBPβ mediates tumour-induced ubiquitin ligase atrogin1/MAFbx upregulation and muscle wasting.
    The EMBO journal, 2011, Aug-16, Volume: 30, Issue:20

    Topics: Animals; Cachexia; Carcinoma, Lewis Lung; Cell Line; Enzyme Inhibitors; Forkhead Box Protein O1; For

2011