Page last updated: 2024-11-04

sb 202190 and Atrophy, Muscle

sb 202190 has been researched along with Atrophy, Muscle in 4 studies

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase

Research Excerpts

Excerpt	Relevance	Reference
"We previously found that p300 mediates cancer-induced muscle wasting by activating C/EBPβ, which then upregulates key catabolic genes."	1.62	Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300. ( Frost, JA; Li, M; Li, YP; Sin, TK; Zhang, G; Zhang, Z; Zhu, JZ; Zuo, Y, 2021)

4 other studies available for sb 202190 and Atrophy, Muscle

Article	Year
Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300. Cancer research, 2021, 02-15, Volume: 81, Issue:4 Topics: Animals; Cachexia; Carcinoma, Lewis Lung; Cells, Cultured; Humans; Imidazoles; Lung Neoplasms; Male;	2021
p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting. American journal of physiology. Cell physiology, 2010, Volume: 298, Issue:3 Topics: Aldehydes; Animals; Autophagy; Cachexia; Cell Line; Dexamethasone; Enzyme Activation; Forkhead Box P	2010
Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:1 Topics: Animals; Autophagy; Blotting, Western; Cell Line; Enzyme Inhibitors; Imidazoles; Lipopolysaccharides	2011
C/EBPβ mediates tumour-induced ubiquitin ligase atrogin1/MAFbx upregulation and muscle wasting. The EMBO journal, 2011, Aug-16, Volume: 30, Issue:20 Topics: Animals; Cachexia; Carcinoma, Lewis Lung; Cell Line; Enzyme Inhibitors; Forkhead Box Protein O1; For	2011