Page last updated: 2024-08-26

sarsasapogenin and Alzheimer Disease

sarsasapogenin has been researched along with Alzheimer Disease in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's5 (62.50)2.80

Authors

AuthorsStudies
Gao, P; Liu, P; Ren, Q; Song, S; Wang, D; Wang, S; Wang, W; Wang, Z; Yao, G; Zhang, Y1
Ge, SL; Huang, J; Li, SL; Ma, L; Wang, R; Wu, Y; Yang, GX1
Li, W; Liu, G; Ma, L; Sun, J; Tang, Y; Wang, R; Wu, Z; Yu, Z; Zhou, M1
Fan, L; Shi, J; Song, C; Wang, H; Wang, J; Yang, S; Zhang, P; Zhang, R; Zhang, Y1
Kashyap, P; Kumar, S; Muthusamy, K; Niranjan, M; Trikha, S1
Bednarikova, Z; Gancar, M; Gazova, Z; Huang, Y; Luo, Y; Ma, L; Spodniakova, B; Tang, Y; Wang, R; Zheng, L1
Gou, LS; Gu, PP; Huang, TT; Liu, YW; Ma, TF; Zhang, YM; Zheng, T1
Song, SJ; Wang, SJ; Wang, W; Wang, WB; Wang, ZD; Yao, GD1

Other Studies

8 other study(ies) available for sarsasapogenin and Alzheimer Disease

ArticleYear
Novel sarsasapogenin-triazolyl hybrids as potential anti-Alzheimer's agents: Design, synthesis and biological evaluation.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Anemarrhena; Animals; Apoptosis; Cell Line; Drug Design; Hippocampus; Humans; Male; Maze Learning; Mice; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Spirostans

2018
Design, synthesis and biological evaluation of 3-piperazinecarboxylate sarsasapogenin derivatives as potential multifunctional anti-Alzheimer agents.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Antioxidants; Drug Design; Humans; Mice; Molecular Docking Simulation; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Piperazines; Protein Aggregates; Rats; RAW 264.7 Cells; Spirostans

2018
Investigation of Anti-Alzheimer's Mechanisms of Sarsasapogenin Derivatives by Network-Based Combining Structure-Based Methods.
    Journal of chemical information and modeling, 2023, 05-08, Volume: 63, Issue:9

    Topics: Alzheimer Disease; Animals; Molecular Docking Simulation; Neurodegenerative Diseases; Spirostans

2023
Smilagenin induces expression and epigenetic remodeling of BDNF in alzheimer's disease.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 118

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Epigenesis, Genetic; Hippocampus; Histones; Humans; Mice; Mice, Transgenic; Neuroblastoma

2023
Sarsasapogenin: A steroidal saponin from Asparagus racemosus as multi target directed ligand in Alzheimer's disease.
    Steroids, 2020, Volume: 153

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Antioxidants; Asparagus Plant; Aspartic Acid Endopeptidases; Biphenyl Compounds; Butyrylcholinesterase; Cell Survival; Electrophorus; Enzyme Inhibitors; Horses; Humans; Ligands; Monoamine Oxidase; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Picrates; Rats; Spirostans

2020
Extracts from Chinese herbs with anti-amyloid and neuroprotective activities.
    International journal of biological macromolecules, 2021, May-15, Volume: 179

    Topics: Abietanes; Alzheimer Disease; Amyloid beta-Peptides; Anemarrhena; Benzofurans; Cell Line; China; Humans; Neuroprotective Agents; Peptide Fragments; Plant Extracts; Salvia miltiorrhiza; Spirostans

2021
Sarsasapogenin attenuates Alzheimer-like encephalopathy in diabetes.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 91

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain Diseases; Cell Line; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3 beta; Hippocampus; Phosphorylation; PPAR gamma; Rats; Spirostans; tau Proteins

2021
Synthesis and evaluation of 26-amino acid methyl ester substituted sarsasapogenin derivatives as neuroprotective agents for Alzheimer's disease.
    Steroids, 2017, Volume: 125

    Topics: Alzheimer Disease; Amino Acids; Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic; Esters; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Neuroprotective Agents; Spirostans

2017