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sarpogrelate and Diseases, Peripheral Vascular

sarpogrelate has been researched along with Diseases, Peripheral Vascular in 4 studies

sarpogrelate: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"Indices of insulin resistance (IR) (fasting immunoreactive insulin (IRI) and calculated homeostasis model assessment (HOMA-R)) and adiponectin were measured before and after 2 weeks of sarpogrelate administration (300 mg/day) in 24 patients (19 men, 76+/-9 years) with PAD."5.12Persistent insulin-sensitizing effects of sarpogrelate hydrochloride, a serotonin 2A receptor antagonist, in patients with peripheral arterial disease. ( Eguchi, M; Hase, M; Hashimoto, A; Kokubu, N; Miura, T; Nagao, K; Nakata, T; Shimamoto, K; Tsuchihashi, K; Tsuzuki, M; Ura, N; Wakabayashi, C; Wakabayashi, T; Yuda, S, 2006)
" Forearm blood flow (FBF) and leg blood flow (LBF) responses to reactive hyperemia (RH) and sublingual administration of nitroglycerin (NTG) were measured using strain-gauge plethysmography."5.12Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease. ( Chayama, K; Goto, C; Higashi, Y; Miyazaki, M; Orihashi, K; Sanada, H; Sueda, T; Yoshizumi, M, 2007)
"Sarpogrelate is a selective 5-hydroxytryptamine (5-HT) receptor subtype 2A antagonist which blocks 5-HT induced platelet aggregation and proliferation of vascular smooth muscle cells."2.80Prospective Randomized Study of Sarpogrelate Versus Clopidogrel-based Dual Antiplatelet Therapies in Patients Undergoing Femoropopliteal Arterial Endovascular Interventions: Preliminary Results. ( Chen, YX; Gu, YQ; Hu, HJ; Li, XQ; Liu, CW; Song, XJ; Tian, HY; Wang, WD; Zhao, JC, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, YX1
Wang, WD1
Song, XJ1
Gu, YQ1
Tian, HY1
Hu, HJ1
Zhao, JC1
Li, XQ1
Liu, CW1
Doggrell, SA1
Kokubu, N1
Tsuchihashi, K1
Yuda, S1
Hase, M1
Eguchi, M1
Wakabayashi, T1
Hashimoto, A1
Nakata, T1
Miura, T1
Ura, N1
Nagao, K1
Tsuzuki, M1
Wakabayashi, C1
Shimamoto, K1
Miyazaki, M1
Higashi, Y1
Goto, C1
Chayama, K1
Yoshizumi, M1
Sanada, H1
Orihashi, K1
Sueda, T1

Reviews

1 review available for sarpogrelate and Diseases, Peripheral Vascular

ArticleYear
The role of 5-HT on the cardiovascular and renal systems and the clinical potential of 5-HT modulation.
    Expert opinion on investigational drugs, 2003, Volume: 12, Issue:5

    Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Carrier Proteins; Coronary Circulat

2003

Trials

3 trials available for sarpogrelate and Diseases, Peripheral Vascular

ArticleYear
Prospective Randomized Study of Sarpogrelate Versus Clopidogrel-based Dual Antiplatelet Therapies in Patients Undergoing Femoropopliteal Arterial Endovascular Interventions: Preliminary Results.
    Chinese medical journal, 2015, Jun-20, Volume: 128, Issue:12

    Topics: Aged; Arterial Occlusive Diseases; Clopidogrel; Female; Fibrinolytic Agents; Humans; Kaplan-Meier Es

2015
Persistent insulin-sensitizing effects of sarpogrelate hydrochloride, a serotonin 2A receptor antagonist, in patients with peripheral arterial disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:11

    Topics: Adiponectin; Aged; Aged, 80 and over; Atherosclerosis; Blood Pressure; Female; Homeostasis; Humans;

2006
Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:4

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Arterial Occlusive Diseases; Biomarkers; Endothelium,

2007