Page last updated: 2024-11-04

sarpogrelate and Disc, Herniated

sarpogrelate has been researched along with Disc, Herniated in 4 studies

sarpogrelate: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"Forty patients with sciatica due to L4-5 or L5-S1 disc herniation were randomly allocated to treatment with the 5-HT2A inhibitor (sarpogrelate 300 mg/day) or nonsteroidal antiinflammatory drugs (NSAIDs; diclofenac 75 mg/day)."5.11New treatment of lumbar disc herniation involving 5-hydroxytryptamine2A receptor inhibitor: a randomized controlled trial. ( Hashimoto, T; Kanayama, M; Oha, F; Shigenobu, K; Yamane, S, 2005)
"Sarpogrelate treatment significantly reduced mechanical allodynia on days 5 and 8 of administration."1.34Sarpogrelate hydrochloride, a 5-HT2A receptor antagonist, attenuates neurogenic pain induced by nucleus pulposus in rats. ( Enyo, Y; Hashizume, H; Inomata, Y; Kawakami, M; Okada, M; Yoshida, M, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kanayama, M2
Hashimoto, T2
Shigenobu, K2
Yamane, S2
Oha, F1
Hashizume, H1
Kawakami, M1
Yoshida, M1
Okada, M1
Enyo, Y1
Inomata, Y1
Sekiguchi, M1
Konno, S1
Kikuchi, S1

Trials

1 trial available for sarpogrelate and Disc, Herniated

ArticleYear
New treatment of lumbar disc herniation involving 5-hydroxytryptamine2A receptor inhibitor: a randomized controlled trial.
    Journal of neurosurgery. Spine, 2005, Volume: 2, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nerve Block; Diclofenac; Epidural Space; F

2005

Other Studies

3 other studies available for sarpogrelate and Disc, Herniated

ArticleYear
Efficacy of serotonin receptor blocker for symptomatic lumbar disc herniation.
    Clinical orthopaedics and related research, 2003, Issue:411

    Topics: Adult; Female; Humans; Hypesthesia; Intervertebral Disc Displacement; Low Back Pain; Magnetic Resona

2003
Sarpogrelate hydrochloride, a 5-HT2A receptor antagonist, attenuates neurogenic pain induced by nucleus pulposus in rats.
    Spine, 2007, Feb-01, Volume: 32, Issue:3

    Topics: Animals; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Pain Measurement;

2007
The effects of a 5-HT2A receptor antagonist on blood flow in lumbar disc herniation: application of nucleus pulposus in a canine model.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2008, Volume: 17, Issue:2

    Topics: Animals; Blood Vessels; Disease Models, Animal; Dogs; Female; Intervertebral Disc; Intervertebral Di

2008