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sarpogrelate and Arteriosclerosis Obliterans

sarpogrelate has been researched along with Arteriosclerosis Obliterans in 6 studies

sarpogrelate: structure given in first source

Arteriosclerosis Obliterans: Common occlusive arterial disease which is caused by ATHEROSCLEROSIS. It is characterized by lesions in the innermost layer (ARTERIAL INTIMA) of arteries including the AORTA and its branches to the extremities. Risk factors include smoking, HYPERLIPIDEMIA, and HYPERTENSION.

Research Excerpts

ExcerptRelevanceReference
"Forty patients who had diabetes with nephropathy and arteriosclerosis obliterans and had already been treated with angiotensin II receptor blocker (n = 40) were randomly assigned to sarpogrelate (300 mg/d; n = 20) or aspirin group (100 mg/d; n = 20)."9.13Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes. ( Ishizuka, T; Ito, S; Mori, T; Nako, K; Ogawa, S, 2008)
"To evaluate the effects of the 5-HT2 receptor antagonist sarpogrelate hydrochloride (sarpogrelate) on platelet responses in arteriosclerosis obliterans (ASO), we examined platelet aggregation and its relationships to platelet-derived growth factor (PDGF), soluble P-selectin (sP-selectin), and transforming growth factor-beta 1 (TGF-beta1)."9.09Effects of sarpogrelate hydrochloride on adenosine diphosphate- or collagen-induced platelet responses in arteriosclerosis obliterans. ( Kariyazono, H; Masuda, H; Nakamura, K; Sakata, R; Yamada, K, 2001)
"Sarpogrelate has a therapeutic effect on patients with atherosclerotic obliterans."6.78Prospective study of sarpogrelate hydrochloride on patients with arteriosclerosis obliterans. ( Liu, J; Liu, P; Qian, S; Ren, S; Wang, W, 2013)
"The aim was to evaluate the significance of arteriosclerosis obliterans-related biomarkers in patients with type 2 diabetes mellitus (T2DM), and to compare the effects of sarpogrelate, eicosapentaenoic acid (EPA) and pitavastatin on these markers."5.27Effects of sarpogrelate, eicosapentaenoic acid and pitavastatin on arterioslcerosis obliterans-related biomarkers in patients with type 2 diabetes (SAREPITASO study). ( Ito, T; Nomura, S; Okuda, Y; Omoto, S; Shouzu, A; Suzuki, M; Taniura, T, 2018)
"Forty patients who had diabetes with nephropathy and arteriosclerosis obliterans and had already been treated with angiotensin II receptor blocker (n = 40) were randomly assigned to sarpogrelate (300 mg/d; n = 20) or aspirin group (100 mg/d; n = 20)."5.13Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes. ( Ishizuka, T; Ito, S; Mori, T; Nako, K; Ogawa, S, 2008)
"To evaluate the effects of the 5-HT2 receptor antagonist sarpogrelate hydrochloride (sarpogrelate) on platelet responses in arteriosclerosis obliterans (ASO), we examined platelet aggregation and its relationships to platelet-derived growth factor (PDGF), soluble P-selectin (sP-selectin), and transforming growth factor-beta 1 (TGF-beta1)."5.09Effects of sarpogrelate hydrochloride on adenosine diphosphate- or collagen-induced platelet responses in arteriosclerosis obliterans. ( Kariyazono, H; Masuda, H; Nakamura, K; Sakata, R; Yamada, K, 2001)
"Sarpogrelate has a therapeutic effect on patients with atherosclerotic obliterans."2.78Prospective study of sarpogrelate hydrochloride on patients with arteriosclerosis obliterans. ( Liu, J; Liu, P; Qian, S; Ren, S; Wang, W, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nomura, S1
Taniura, T1
Shouzu, A1
Omoto, S1
Suzuki, M1
Okuda, Y1
Ito, T1
Higashi, Y1
Fujita, M1
Origasa, H1
Miyata, T1
Matsuo, H1
Naritomi, H1
Shigematsu, H1
Ren, S1
Qian, S1
Wang, W1
Liu, J1
Liu, P1
Yamakawa, J1
Takahashi, T1
Itoh, T1
Kusaka, K1
Kawaura, K1
Wang, XQ1
Kanda, T1
Ogawa, S1
Mori, T1
Nako, K1
Ishizuka, T1
Ito, S1
Nakamura, K1
Kariyazono, H1
Masuda, H1
Sakata, R1
Yamada, K1

Trials

5 trials available for sarpogrelate and Arteriosclerosis Obliterans

ArticleYear
Effects of sarpogrelate, eicosapentaenoic acid and pitavastatin on arterioslcerosis obliterans-related biomarkers in patients with type 2 diabetes (SAREPITASO study).
    Vascular health and risk management, 2018, Volume: 14

    Topics: Adiponectin; Aged; Aged, 80 and over; Ankle Brachial Index; Arteriosclerosis Obliterans; Biomarkers;

2018
Prospective study of sarpogrelate hydrochloride on patients with arteriosclerosis obliterans.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2013, Volume: 19, Issue:1

    Topics: Aged; Ankle Brachial Index; Arteriosclerosis Obliterans; Cardiovascular Agents; Chi-Square Distribut

2013
A novel serotonin blocker, sarpogrelate, increases circulating adiponectin levels in diabetic patients with arteriosclerosis obliterans.
    Diabetes care, 2003, Volume: 26, Issue:8

    Topics: Adiponectin; Aged; Arteriosclerosis Obliterans; Diabetes Mellitus, Type 2; Female; Humans; Intercell

2003
Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:2

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Arteriosclerosis Obliterans; Aspirin; Ch

2008
Effects of sarpogrelate hydrochloride on adenosine diphosphate- or collagen-induced platelet responses in arteriosclerosis obliterans.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2001, Volume: 12, Issue:5

    Topics: Adenosine Diphosphate; Aged; Arteriosclerosis Obliterans; Case-Control Studies; Collagen; Female; Hu

2001

Other Studies

1 other study available for sarpogrelate and Arteriosclerosis Obliterans

ArticleYear
Study design of SEASON registry: prospective Surveillance of cardiovascular Events in an Antiplatelet-treated arterioSclerosis Obliterans patients in JapaN )SEASON).
    International heart journal, 2010, Volume: 51, Issue:5

    Topics: Arteriosclerosis Obliterans; Cardiovascular Diseases; Humans; Japan; Platelet Aggregation Inhibitors

2010