sarpogrelate has been researched along with Alloxan Diabetes in 7 studies
sarpogrelate: structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment with sarpogrelate improved ROS/NO imbalance in glomeruli, suppressed platelet aggregation in glomeruli, reduced platelet-derived microparticles, increased serum adiponectin level and reduced the level of albuminuria, compared with non-treated diabetic rats." | 3.74 | Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy. ( Arakawa, S; Fujimoto, S; Haruna, Y; Kashihara, N; Kobayashi, S; Komai, N; Namikoshi, T; Sasaki, T; Satoh, M; Tomita, N, 2008) |
| "The combined treatment of sustained-release basic fibroblast growth factor (Sr-bFGF) and a 5-hydroxytryptamine(2A) blocker, sarpogrelate, was evaluated to see whether it reversed the impaired collateral circulation in diabetic (DM) mouse hindlimb ischemia." | 3.74 | New therapeutic approach for impaired arteriogenesis in diabetic mouse hindlimb ischemia. ( Arai, Y; Bir, SC; Esaki, J; Fujita, M; Hirose, K; Huang, Y; Ikeda, T; Komeda, M; Marui, A; Sakaguchi, H; Tabata, Y, 2008) |
| "Treatment with sarpogrelate significantly lowered fasting glucose levels with corresponding increase in insulin levels." | 1.32 | Effect of sarpogrelate on altered STZ-diabetes induced cardiovascular responses to 5-hydroxytryptamine in rats. ( Bodiwala, DN; Goyal, RK; Umrani, DN, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Fouad Shalaby, MA | 1 |
| Abd El Latif, HA | 1 |
| El Yamani, M | 1 |
| Galal, MA | 1 |
| Kamal, S | 1 |
| Sindi, I | 1 |
| Masaood, R | 1 |
| Iwabayashi, M | 1 |
| Taniyama, Y | 1 |
| Sanada, F | 1 |
| Azuma, J | 1 |
| Iekushi, K | 1 |
| Kusunoki, H | 1 |
| Chatterjee, A | 1 |
| Okayama, K | 1 |
| Rakugi, H | 1 |
| Morishita, R | 1 |
| Yamada, K | 1 |
| Niki, H | 1 |
| Nagai, H | 1 |
| Nishikawa, M | 1 |
| Nakagawa, H | 1 |
| Umrani, DN | 1 |
| Bodiwala, DN | 1 |
| Goyal, RK | 1 |
| Kobayashi, S | 1 |
| Satoh, M | 1 |
| Namikoshi, T | 1 |
| Haruna, Y | 1 |
| Fujimoto, S | 1 |
| Arakawa, S | 1 |
| Komai, N | 1 |
| Tomita, N | 1 |
| Sasaki, T | 1 |
| Kashihara, N | 1 |
| Bir, SC | 1 |
| Fujita, M | 1 |
| Marui, A | 1 |
| Hirose, K | 1 |
| Arai, Y | 1 |
| Sakaguchi, H | 1 |
| Huang, Y | 1 |
| Esaki, J | 1 |
| Ikeda, T | 1 |
| Tabata, Y | 1 |
| Komeda, M | 1 |
| Kodama, M | 1 |
| Takimoto, Y | 1 |
7 other studies available for sarpogrelate and Alloxan Diabetes
| Article | Year |
|---|---|
Therapeutic activity of sarpogrelate and dopamine D
Topics: Animals; Blood Glucose; Bromocriptine; Cabergoline; Diabetes Mellitus, Experimental; Diabetic Nephro | 2021 |
Role of serotonin in angiogenesis: induction of angiogenesis by sarpogrelate via endothelial 5-HT1B/Akt/eNOS pathway in diabetic mice.
Topics: Angiogenesis Inducing Agents; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic An | 2012 |
Serotonin potentiates high-glucose-induced endothelial injury: the role of serotonin and 5-HT(2A) receptors in promoting thrombosis in diabetes.
Topics: Animals; Aspirin; Cells, Cultured; Cilostazol; Diabetes Mellitus, Experimental; Fibrinolytic Agents; | 2012 |
Effect of sarpogrelate on altered STZ-diabetes induced cardiovascular responses to 5-hydroxytryptamine in rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Myocardium; Platelet Aggregation; Rats; Rec | 2003 |
Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adiponectin; Albuminuria; Animals; Blood Platelets; Deoxyguanosine; Dia | 2008 |
New therapeutic approach for impaired arteriogenesis in diabetic mouse hindlimb ischemia.
Topics: Animals; Base Sequence; Collateral Circulation; Delayed-Action Preparations; Diabetes Mellitus, Expe | 2008 |
Influence of 5-hydroxytryptamine and the effect of a new serotonin receptor antagonist (sarpogrelate) on detrusor smooth muscle of streptozotocin-induced diabetes mellitus in the rat.
Topics: Animals; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smo | 2000 |